Results 51 to 60 of about 21,192 (293)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

Influence of new media use on patients′ healthcare-seeking behavior

Zhongguo gonggong weisheng, 2022
ObjectiveTo examine the status of new media dependence and healthcare-seeking behavior among patients and to explore the influence and mechanism of new media use on the patients′ healthcare-seeking behavior.
Yu LEI
doaj   +1 more source

Proposing heightened emotions social media dependency model: review and extension of media system dependency theory

Annals of the International Communication Association
Abstract This theoretical paper extends Media System Dependency theory to better account for affective dynamics in today’s social media environment. We introduce the Heightened Emotions Social Media Dependency Model to explain how pervasive ambiguity contributes to elevated emotional states, which in turn intensify individuals ...
Kikuko Omori, Joo-Young Jung, Stephen Croucher   +2 more
openaire   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

EVOLUSI TEORI KETERGANTUNGAN SISTEM MEDIA MENJADI TEORI INFRASTRUKTUR KOMUNIKASI

, 2013
This article deals with a matter of evolution theory in the study of science communications. Object of theory discussed is Media System Dependency Theory which introduced by Ball-Rokeach. This article is focused to overview: 1).
Mahmudah, Dede
core   +1 more source

How in-U.S. Chinese college sudents consume Covid-19 information on social media: examining the relationship between media credibility and media dependency [PDF]

, 2021
In the 2019/2020 academic year, around 370,000 Chinese students studied at U.S. colleges and universities. During the COVID-19 pandemic, social media serve as an important channel for in-U.S.
Liu, Siyu
core  

Editorial Journalism and Environmental Issues in the Majority World

International Journal of Communication, 2022
Prior research suggests that reliance on news media is dramatically increased during a public health crisis because people need more information to reduce their anxiety levels.
Shafiq Ahmad Kamboh, Muhammad Ittefaq, Muhammad Yousaf   +2 more
doaj  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source