From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan+2 more
wiley +1 more source
An Ecological Perspective on the Media and Youth Development [PDF]
From an ecological perspective, daily activities are both a cause and a consequence of youth development. Research on youth activities directs attention to the processes through which daily activities may have an impact on youth, including (a) providing chances to learn and practice skills, (b) serving as a forum for identity development, (c ...
Aryn M. Dotterer+2 more
openaire +3 more sources
The Development of New Casting Alloys Intended for Operation Under Extreme Conditions and Some Techniques of Making Castings From Them [PDF]
The article studies new heat-resistant and wear resistant materials for operation under extreme conditions, especially in the power industry. The methods that improve the quality of a metal in metal castings through the influence of alloying elements on ...
Fedorov, G. (Grigoriy)+2 more
core
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson+7 more
wiley +1 more source
Website development on herbal plant diversity as media in Kurikulum Merdeka
Local wisdom which is the theme of the project to strengthen the character of Pancasila in the Merdeka Curriculum includes the fading of ancestral culture such as traditional vegetable medicine. Although schools have limited resources for teaching local
Ariftania Madrin, R. Ratnawati
doaj +1 more source
The Evolution of Media Development: the Media Development Model in a Changing World
The origins of Media Development can be found in Post WW2 Europe and the industry grew as a more significant aspect of international aid work in the 1980s and the 1990s, following the end of the Cold War and the collapse of the former Soviet Union. It was hoped that exporting the concept of a free and independent press would foster democracy in post ...
openaire +4 more sources
The Development of Module to Increase Critical Thinking Skill [PDF]
Penelitian ini bertujuan untuk mengetahui bagaimana mengembangkan modul matematika serta efektifitasnya ditinjau dari kemampuan berpikir kritis matematis siswa. Subjek penelitian adalah siswa kelas VII SMP IT Bina Insani Metro. Penyusunan modul dilakukan
Ikashaum, F. (Fertilia)
core
Digital Flipbook Imunopedia (DFI): A Development in Immune System e-Learning Media
Immune system content along with body defense mechanism tends to be an abstract content that is hard to comprehend by students. Digital flipbook learning media become an innovative learning medium to facilitate the immune system content understanding for
R. H. Ristanto+4 more
semanticscholar +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li+3 more
wiley +1 more source
Achievements under diverse, sometimes impossible conditions
What is the role of the media within society? Does that role differ within developing countries (DCs)? Are dichotomous representations of societies and their media viable? These are just some of the questions thrown up by two very challenging collections
Robbie Robertson
doaj +1 more source