Results 151 to 160 of about 22,247,482 (397)

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Researching Media Assistance as a Tool of Democratisation and State building in Post Conflict Societies – Lessons from the Case of Bosnia and Herzegovina [PDF]

open access: yesGlobal Media Journal: German Edition, 2012
This paper aims to give insights into my research on media assistance and its effects on democratisation and state building processes in Bosnia and Herzegovina (Bosnia).
Nidzara Ahmetasevic
doaj  

Expression and DNA methylation of 20S proteasome subunits as prognostic and resistance markers in cancer

open access: yesMolecular Oncology, EarlyView.
Comprehensive analysis of genomic mutations, gene expression, DNA methylation, and pathway analysis of TCGA data was carried out to define cancer types in which proteasome subunits expression is associated with worse survival. Albeit the effect of specific proteasome subunits on cellular function, the main role of the proteasome is better evaluated ...
Ruba Al‐Abdulla   +5 more
wiley   +1 more source

PENGEMBANGAN MEDIA PEMBELAJARAN COMPUTER AIDED DRAFTING AND DESIGN (CADD) BERBANTUAN KOMPUTER UNTUK MENINGKATKAN PRESTASI BELAJAR SISWA KELAS XI DI SMK MUHAMMADIYAH PRAMBANAN [PDF]

open access: yes, 2012
Penelitian ini bertujuan untuk membuat media pembelajaran CADD berbantuan komputer, mengetahui kelayakan media video, dan mengetahui pengaruh penerapan media pembelajaran berbantuan komputer terhadap prestasi belajar siswa kelas XI Jurusan Teknik Mesin ...
Basit , Wahyudi
core  

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Communications Policy, Media Development, and Convergence [PDF]

open access: yes
In the deliberations of scholars, policy analysts, and policy makers, television has exceptional power and influence. Yet the historical record shows that television has not changed the economics of attention for large populations in the course of their ...
Douglas A. Galbi
core  

LEARNING MEDIA DEVELOPMENT TEST OF TRANS-DIMENSIONAL PICTURE OBJECT (TRANS-DIMENSIONAL OBJEK GAMBAR/TDOG) IN THE OF FIRST BUILDING CONSTRUCTION AND DRAWING COURSE (KONSTRUKSI BANGUNAN/KBM I) [PDF]

open access: yes, 2012
The competency of KBM I course contained a concept of complicated building structures, especially for students whose background of Senior High School.
Sugiarto
core  

MicroRNA 196a contributes to the aggressiveness of esophageal adenocarcinoma through the MYC/TERT/NFκB axis

open access: yesMolecular Oncology, EarlyView.
mir‐196a promotes Esophagus Adenocarcinoma aggressiveness. On one hand, mir‐196a targets the valosin‐containing protein (VCP) mRNA, causing the accumulation of c‐MYC protein that leads to high amounts of TERT. On the other hand, mir‐196a targets the inhibitor of NFκB (NFKBIA).
Jesús García‐Castillo   +8 more
wiley   +1 more source

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