Results 161 to 170 of about 4,380,329 (401)
Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine
Molecular Oncology, EarlyView.The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu +18 more
wiley +1 more source
When Anonymous Controlling Professional Media: A Marginal Voice in Press Freedom Country [PDF]
, 2014 The emergence of citizen journalism get a skeptical response from professional journalists based on several reasons such as un-institutional, subjective and nonprofessional (O¨rnebring, 2013; Allan, 2009; Moyo, 2009).
Nurul, Hasfi
core
A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression
Molecular Oncology, EarlyView.Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak +8 more
wiley +1 more source
ASSOCIATIVE POTENTIAL OF PRECEDENT TEXTS IN MEDIA DISCOURSE [PDF]
, 2019 Карпенко Светлана Михайловна +1 more
openalex +1 more source
The democratic rhetoric of the austerity measures [PDF]
, 2013 The main purpose of this paper is to make an analysis of the policy-legitimizing discourses of the political-economic executive in Portugal considering the social and economic crisis thecountry is going through, and how this democratic legitimation is ...
Van Vossole, Jonas
core +1 more source
"Xylella is the Enemy that Must be Fought": Representations of the X. Fastidiosa Bacterium in the Media Discourse. [PDF]
Corpus Pragmat, 2022 Pavlović TV, Đorđević D.
europepmc +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Polish-Lithuanian Rhetoric in Media Discourse
Studies in Logic, Grammar and RhetoricThis study examines how Polish-Lithuanian political myths, stereo- types, and historical phobias are reproduced and transformed in contemporary media discourse. Although many of these narratives originate in nineteenth- and early twentieth-century nation-
Berštanska Katažyna
doaj +1 more source