Results 221 to 230 of about 4,306,154 (354)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

"Shaping ChatGPT into my Digital Therapist": A thematic analysis of social media discourse on using generative artificial intelligence for mental health. [PDF]

Digit Health
Luo X, Ghosh S, Tilley JL, Besada P, Wang J, Xiang Y.   +5 more
europepmc   +1 more source

Género Y Política: Análisis Del Discurso Mediático De Hispanoamérica Y España|Gender and Politics: Media Discourse Analysis of Latin America and Spain

, 2013
Laura Teruel Rodríguez
openalex   +1 more source

Hate Speech Patterns in Social Media: A Methodological Framework and Fat Stigma Investigation Incorporating Sentiment Analysis, Topic Modelling and Discourse Analysis

, 2023
Vajisha Udayangi Wanniarachchi, Chris Scogings, Teo Sušnjak, Anuradha Mathrani   +3 more
openalex   +2 more sources

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Journalists in a circular economy: Stakeholders' engagement in the media discourse on single-use plastics during the COVID-19 pandemic. [PDF]

Heliyon
Krawczyk A, Goc A, Pellegrini A, Jaguszewska N, Salas BO, Bukowski M, Grodzińska-Jurczak M.   +6 more
europepmc   +1 more source

Chinese News Media Discourse of Doulas and Doula Care. [PDF]

J Perinat Educ, 2018
Dai Z.
europepmc   +1 more source

Framing and Metaphor in Media Discourse

Tetsuta Komatsubara
openalex   +2 more sources

Norway’s involvement in the transatlantic slave trade: a discourse analysis of media coverage and implications for education [PDF]

Paul Thomas, Jocelyne Von Hof
openalex   +1 more source