Results 111 to 120 of about 1,725,195 (297)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Diminished, Enduring, and Emergent Diversity Policy Concerns in an Evolving Media Environment

open access: yesInternational Journal of Communication, 2011
This article examines the evolution of media diversity policy concerns in response to the changing technological and institutional dynamics of the media environment.
Philip M. Napoli
doaj   +2 more sources

Fostering Media Education Competence Focusing on Diversity

open access: yesMedienimpulse
Societal processes in mediatization and diversity increase demands on initial teacher education, requiring preservice teachers to develop media education competence focusing on diversity.
Antonia Halsch, Silke Grafe
doaj   +1 more source

DIVERSITY EFFORTS IN INDEPENDENT SCHOOLS [PDF]

open access: yes, 2001
When it comes to diversity, many high-end institutions--including those in education, politics, and media--have been slow to change and reluctant to promote people who do not fit a certain profile.
Brosnan, Michael
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Diversity disorders: Ethnicity and newsroom cultures [PDF]

open access: yesConflict & Communication Online, 2009
Sweden, as many other European countries, has been engaged in the debate concerning the relationships between social cohesion and the media. The article examines the tension between officially expressed attitudes and diversity goals of Swedish newsrooms ...
Gunilla Hultén
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Pollinator Diversity and Foraging Dynamics on Monsoon Crop of Cucurbits in a Traditional Landscape of South Indian West Coast [PDF]

open access: yes, 2017
Studies on insect pollinator ecology and dynamics are very rarely carried out in traditional Indian agriculture landscapes. Indiscriminate landscape changes in the rural areas and tendencies towards crop monocultures can have significant effects on ...
V, R. T. (RAMACHANDRA)
core  

Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics

open access: yesFEBS Open Bio, EarlyView.
Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini   +2 more
wiley   +1 more source

Phase retrieval via media diversity

open access: yesInverse Problems
Abstract This work studies phase retrieval in the Fresnel regime, aiming to recover the phase of an incoming wave from multi-plane intensity measurements behind different types of linear and nonlinear media. We show that unique phase retrieval can be achieved by utilizing intensity data produced by multiple media.
Yan Cheng, Kui Ren, Nathan Soedjak
openaire   +2 more sources

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