Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
“Let Them Stay There”: COVID-19 and Zimbabwe’s Indignation Against Return Migrants and Travelers
This paper explains the indignation against and stigmatization of return migrants and travelers when Zimbabwe first recorded cases of COVID-19 in 2020.
Chipo Hungwe, Zvenyika Mugari
doaj +1 more source
Information feedback and mass media effects in cultural dynamics [PDF]
We study the effects of different forms of information feedback associated with mass media on an agent-agent based model of the dynamics of cultural dissemination. In addition to some processes previously considered, we also examine a model of local mass
Cosenza, M. G. +4 more
core +1 more source
Genetic Diversity Evaluation of Moringa Oleifera, Lam From East Flores Regency Using Marker Random Amplified Polymorphic DNA (RAPD) and Its Relationship to Chemical Composition and in Vitro Gas Production [PDF]
The research objective was to evaluate the genetic diversity of Moringa oleifera, Lam (MO) and its relationship to chemical composition and in vitro gas production (IVGP). Fresh MO leaves were kept frozen in ice gels pack until laboratory analysis.
Kleden, M. M. (Markus) +3 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Media Discourse and the Feminization of Poverty [PDF]
Source diversity models suggest that by using non-conventional, non-official sources for news content, the prevailing perceptions about poor people and their needs would be undermined in news coverage.
Manning-Miller, Carmen L.
core +1 more source
Do Media Monsters Devour Diversity? [PDF]
Politicians and critics have long lamented that the rise of huge media conglomerates means the death of diversity in newspapers and on the airwaves. But research suggests that media conglomeration, however distasteful, does not necessarily reduce diversity.
Joshua Gamson, Pearl Latteier
openaire +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Understanding the multiculturalism values through social media among Indonesian youths
The diversity of Indonesian people can be a problem when they do not have a sense of brotherhood based on the diversity of religion, culture, language and ethnic groups. Understanding diversity is known by young people through various media outlets. This
Tuti Budirahayu +2 more
doaj +1 more source

