Results 121 to 130 of about 1,719,395 (305)

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

L'Ètica periodística en el context postsoviètic: el cas de la televisió a Rússia [PDF]

open access: yes, 2011
ètica periodística, televisió russa, televisió soviètica, NTV, Putin, censura.Media ethics in the post-Soviet context: the case of Russian television The dissolution of the Soviet Union, the fall of the Soviet ideological system, the entrance of the ...
Guerrero-Solé, Frederic
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Life under Decree No. 29 of 2010: The Fiji Media Development Decree

open access: yesPacific Journalism Review, 2010
This article examines the domestic and regional impact of a punitive media law introduced in Fiji in June. Decree No. 29 of 2010, the Media Industry Development Decree, is the first of its kind in the South Pacific.
Shailendra Singh
doaj  

CASE STUDY ON MEDIA ETHICS IN FRANCE

open access: yesAnnals of the University of Oradea: Economic Science
Carried out as part of an educational project by Hugo Saez under the supervision of Doina Muresanu, this case study focuses on ethical aspects linked to the field of journalism.
Hugo SAEZ, Doina MURESANU
doaj   +1 more source

Using drama to introduce ethics to technology students and practitioners [PDF]

open access: yes, 2009
In this poster we describe the use of Joe Penhall's play 'Landscape with Weapon' as a resource to teach ethics to students and practitioners in technology. 'Landscape with Weapon' is a play in three acts that revolve around issues confronting an engineer
Ferreira, Giselle, Monk, John
core  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Pengaruh Money Ethics Terhadap Tax Evasion Dengan Intrinsic Dan Extrinsic Religiosity Sebagai Variabel Moderating [PDF]

open access: yes, 2014
Penelitian ini dilakukan untuk mengetahui pengaruh money ethics terhadap tax evasion dan juga untuk mengetahui dampak intrinsic dan extrinsic religiosity sebagai variabel moderating dalam pengaruhnya terhadap money ethics dan tax evasion.
Mangoting, Y. (Yenni)   +1 more
core  

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