Results 51 to 60 of about 552,023 (254)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Framing of and Attention to COVID-19 on Twitter: Thematic Analysis of Hashtags

Journal of Medical Internet Research, 2021
BackgroundAlthough past research has focused on COVID-19–related frames in the news media, such research may not accurately capture and represent the perspectives of people from diverse backgrounds.
Iman Tahamtan, Devendra Potnis, Ehsan Mohammadi, Laura E Miller, Vandana Singh   +4 more
doaj   +1 more source

Reinventing discovery learning: a field-wide research program [PDF]

, 2017
© 2017, Springer Science+Business Media B.V., part of Springer Nature. Whereas some educational designers believe that students should learn new concepts through explorative problem solving within dedicated environments that constrain key parameters of ...
Abrahamson, D, Kapur, M
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

`Human clones talk about their lives': Media representations of assisted reproductive and biogenetic technologies [PDF]

, 2007
This article examines New Zealand print media representations of assisted reproductive and related biogenetic technologies, conceptualized as the products of a concordance of interest between media workers and reproductive specialists, biogenetic ...
Michelle, Carolyn
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Trends in American Newspaper Coverage of Autism [PDF]

, 2019
The public\u27s understanding of disabilities is cultivated via several media resources, including news media. Disability scholars often cite negative representations of disabilities in mass media, yet analyses of newspaper journalists\u27 coverage of ...
Miller, Allison
core   +1 more source

Framing alleged Islamist plots: a case study of British press coverage since 9/11 [PDF]

, 2015
In the decade post 9/11 , the UK terrorist threat was associated with a series of high profile counter terrorism operations, linked to specific plots. These terrorism related episodes received significant media attention and, as a consequence, were a ...
Allen C., Allen C., Allen C., Ansari F., Archetti C., Awan A. N., Baker-Beall C., Brinson M., Carruthers S., Fairclough N., Gitlin T., Graber D. A., Hall S., Home Office, Hoskins A., Iyengar S., Jackson R., Jamie Matthews, Karim H. K., Marranci G., McGhee D., Norris P., Perse E. M., Picard R. G., Poole E., Tankard J. W., van Dijk T. A., Van Gorp B., Xigen L., Zelizer B.   +29 more
core   +1 more source

Media Framing and Framing by Politicians

Journal of Government and Politics, 2019
There are substantial amount of academic research regarding to how media do the framing on certain issue. However, empirical research on the framing interactions is still difficult to find. This study endeavors to fill the void by questioning the mutual influences between media framing and framing by politicians on a specific issue during the political
openaire   +2 more sources

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source