Results 131 to 140 of about 132,934 (305)

Media sources and information needs of displaced and non-displaced Syrians

open access: yes, 2020
Using the Syrian war as a case study, this article examines the theoretical frameworks of media dependency and selective exposure during the war. Through a survey of 2,192 Syrians living in Syria, Lebanon, Jordan, and Turkey during the conflict, the ...
Kozman, Claudia, Melki, Jad
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Into The New Millennium: The Role of Indigenous Media in Australia

open access: yes, 1998
This article explores the nature of Indigenous media production in Australia in relation to a two-year study — the Millennium Project — which has begun to explore the implications and possibilities offered by new media technologies in Indigenous ...
Michael Meadows   +3 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Support frameworks for the use of social media by emergency management organisations: Policy report

open access: yes, 2015
This policy seeks to improve knowledge sharing across Australian emergency management organisations about the effective uses of social media for crisis communication.
Flew, Terry   +11 more
core  

Understanding the democratic role of media ownership transparency

open access: yes
Published online: 13 September 2024This chapter discusses the evolution of media ownership transparency requirements in Europe. Transparency of media ownership plays an important democratic function in society as it allows citizens to be critical about ...
CHRISTOPHOROU, Christophoros   +1 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Africa: Media Systems

open access: yes, 2010
This entry concentrates on media systems in countries of Sub-Saharan Africa. The Sub- Saharan media system was born in the colonial era. Following the partition of Africa in Berlin in 1884, the colonial era saw the establishment of mass media systems ...
Mano, W.
core   +1 more source

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