Results 231 to 240 of about 1,342,552 (347)

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

Advanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen, Ling Wang, Hongmei Fan, Lisheng Li, Lingyu Zhang, Ruoxin Li, Fang Liu, Fuli Wen, Yunbin Ye, Chuanzhong Huang   +9 more
wiley   +1 more source

Digital child protection in social networks: age verification and age-tiered regulation in Europe. [PDF]

Child Adolesc Psychiatry Ment Health
Köhler-Dauner F, Peter L, Sitarski E, Chauviré-Geib K, Haag AC, Fegert JM.   +5 more
europepmc   +1 more source

Multifunctional Gelatin‐Based Smart Films Integrating Thermochromic Encryption, Temperature‐Regulated Photothermal Management, Reprocessability, and Biodegradability for Sustainable Applications

Advanced Science, EarlyView.
Multifunctional gelatin films synergizing thermochromic encryption, self‐regulating photothermal management, and closed‐loop recyclability offer sustainable solutions for intelligent packaging. ABSTRACT Multifunctional gelatin‐based smart films are engineered by incorporating hyperbranched polyglycerol (HBPG) as a plasticizer, dialdehyde β‐cyclodextrin
Yuehong Zhang, Chen Yang, Langlang Dai, Leipeng Liu, Vijay Kumar Thakur   +4 more
wiley   +1 more source

Freedom Of Speech Vs. Hate Speech On Social Media: Legal Boundaries And Challenges

Farhana Aziz Rana
openalex   +2 more sources

Commodity risk assessment of <i>Petunia</i> spp. and <i>Calibrachoa</i> spp. unrooted cuttings from Uganda. [PDF]

EFSA J
EFSA Panel on Plant Health (PLH), Civera AV, Baptista P, Berlin A, Chatzivassiliou E, Cubero J, Cunniffe N, de la Peña E, Desneux N, Di Serio F, Filipiak A, Gonthier P, Hasiów-Jaroszewska B, Jactel H, Landa BB, Maistrello L, Makowski D, Milonas P, Papadopoulos NT, Susi H, van der Gaag DJ, Lacomme C, Debode J, Navas-Cortes JA, Akrivou A, Kritikos C, Kormpi M, Papachristos D, Reppa C, Antonatos S, Beris D, Schulz OM, Lombardo MF, Gardi C, Potting R.   +34 more
europepmc   +1 more source

MELEGROS: Monolithic Elephant‐Inspired Gripper with Optical Sensors

Advanced Science, EarlyView.
MELEGROS is a monolithic, elephant‐inspired soft gripper integrating 3D‐printed optical sensors within a pneumatically actuated lattice. Simulation‐guided design decouples tactile and proprioceptive sensing. Characterized through grasping tests, MELEGROS can reach, scoop, and grasp, showcasing a paradigm where fully embedded sensing and continuous ...
Petr Trunin, Diana Cafiso, Anderson Brazil Nardin, Trevor Exley, Lucia Beccai   +4 more
wiley   +1 more source

Media freedom and independence: The European judicial approach in fourteen countries

, 2012
Sebastian Müller, Christoph Gusy, Bart Van Besien, Pierre-François Docquir   +3 more
openalex   +1 more source

Why science must speak differently. [PDF]

Infect Agent Cancer
Branda F, Campanozzi LL, Scarpa F, Tambone V, Ciccozzi M.   +4 more
europepmc   +1 more source

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

Advanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

Due to Increased Immune Therapies, Are Sensitized Heart Transplant Recipients at Increased Risk for Malignancies? [PDF]

Transpl Int
Tsuji M, Kittleson MM, Chang DH, Kransdorf EP, Nikolova AP, Stern LK, Lee M, Kobashigawa JA.   +7 more
europepmc   +1 more source