Results 81 to 90 of about 3,159 (261)
CONTEXTO: Atualmente há um crescente interesse por instrumentos de avaliação em saúde produzidos e validados em todo o mundo. Apesar disso, ainda não temos no Brasil instrumentos que avaliem o impacto da doença venosa crônica na vida de seu portador ...
Flávia de Jesus Leal +6 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Fansubbing de l'espanyol al xinès : organització, rols i normes en l'escriptura col·laborativa
Objectiu: documentar i analitzar la cooperació en línia d'una comunitat digital que subtitula sèries i pel·lícules hispanes al xinès; estudiar-ne els rols i les funcions, la cadena de treball, els espais virtuals, les estratègies d'autoregulació i les ...
Zhang, Tian Leticia, Cassany, Daniel
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
A vision for responsible AI integration in citizen science
The integration of Artificial Intelligence (AI) into Citizen Science (CS) is transforming how communities collect, analyze, and share data, offering opportunities for enhanced efficiency, accuracy, and scalability of CS projects.
Maryam Lotfian +6 more
doaj +1 more source
Fansubbing del español al chino : organización, roles y normas en la escritura colaborativa
Objetivo: documentar y analizar la cooperación en línea de una comunidad digital que subtitula series y películas hispanas al chino, estudiando los roles y las funciones, la cadena de trabajo, los espacios virtuales, las estrategias de autorregulación y ...
Zhang, Tian Leticia, Cassany, Daniel
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
The mycobacterial CIII‐CIV respiratory supercomplex is an obligate assembly, encompassing several subunits of unknown functions. We have characterized the intracellular subunit AscF, and show that it is unlikely to be a sensor for metals or nucleotides, but is required for growth on nonfermentable energy sources, and likely works as an adapter for ...
Eni Rile +8 more
wiley +1 more source
Identification of the plant mitochondrial OrfX protein: A mass spectrometry approach
The mitochondrial genome of plants contains an open reading frame, orfx, which encodes a rare protein that has so far escaped mass spectrometric detection. The protein resembles the c‐subunit of bacterial twin‐arginine‐motif‐dependent protein translocases (TatC).
Matthias Döring +3 more
wiley +1 more source

