Results 61 to 70 of about 18,230,302 (195)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
A group of Finnish journalism students travelled to Zambia, Africa in November 2007. The field trip was a culmination for a course in journalism on developing countries.
Jaana Hujanen
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Globalization encourages innovation in service providers such as freelance providers of goods delivery services (jastip). Jastip exists through social media and it can be seen that it is still in demand by consumers to get what they want.
Muhammad Aufal Haq +3 more
doaj +1 more source
Le fonds Jean Lattes : une archive photographique en construction
The donation in 2011, by his widow Janine Lattes, of more than 180,000 photos taken by the photojournalist Jean Lattes (1917 - 1996) to the archive service of the Yvelines department forced its archivists to reflect on their practice.
Angelina Meslem +2 more
doaj +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
Inhibition of dipeptidyl peptidase 7 impairs lysophagy in LLOMe‐treated HepG2 cells
DPP7 inhibition delays ubiquitin‐dependent lysophagy by attenuating ubiquitin accumulation and the recruitment of SQSTM1 and LC3 to damaged lysosomes, resulting in delayed clearance of damaged lysosomes and impaired restoration of lysosomal homeostasis. Created using FigureLabs (Certificate ID: FL‐PUB‐20260922‐Z99XNX).
Na Yeon Park +8 more
wiley +1 more source
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Kompetensi Jurnalis Freelance pada era jurnalistik kontemporer: Studi deskriptif kualitatif terhadap jurnalis Freelance [PDF]
Seiring dengan kemajuan teknologi dan perkembangan media sosial, muncul penulis-penulis yang memilih menjadi freelance, mereka tidak terikat dengan satu media saja. Kompetensi seorang jurnalis, akan ditunjukkan melalui berita yang ditulisnya.
Fitriani, Anisa
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