Results 131 to 140 of about 16,268,438 (244)
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Freelance/Travel Writing Workshop [PDF]
Members of the Belmont community are invited to join published authors and freelance journalists for a workshop on freelance journalism and travel-inspired writing, journalistic, personal, and ...
D\u27Souza, Tony +4 more
core
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
AI-Powered Campaign Management: The Future of Freelance Media Buying
AI-Powered Campaign Management: The Future of Freelance Media Buying examines how artificial intelligence is transforming the way freelance media buyers manage digital advertising campaigns. It highlights how tools like Smart Bidding, automation scripts, and AI-driven creatives enable solo professionals to deliver agency-level results, scale operations
openaire +1 more source
PERSONAL BRANDING OF FREELANCE MAKE UP ARTIST (MUA) IN PEKANBARU CITY ON INSTAGRAM SOCIAL MEDIA
Searching for MUA services in the digital era is now easy, with many choices on social media such as Instagram, which allows searches based on domicile, price, characteristics or quality. This research aims to analyze the personal branding of freelance MUAs in Pekanbaru via Instagram, using Montoya's personal branding theory with eight indicators ...
null Suci Shinta Lestari +1 more
openaire +1 more source
Media History and Social Regulation Mod 2 Unit 11
Module 2 discusses key features and developments in media history, focusing on the histories of print and audio-visual media. The module examines issues in the debates that govern scholarly, ethical and political thinking about the actual or desired ...
Department of Media and Communications
core
Fansubbing from Spanish to Chinese : organization, roles and norms in collaborative writing
Objective. This paper documents and analyzes how the members of an online community of fansubbers collaborate to subtitle Hispanic series and films in Chinese.
Zhang, Tian Leticia, Cassany, Daniel
doaj
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source

