Results 111 to 120 of about 15,352 (273)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

PERSONAL BRANDING OF FREELANCE MAKE UP ARTIST (MUA) IN PEKANBARU CITY ON INSTAGRAM SOCIAL MEDIA

Jurnal Netnografi Komunikasi
Searching for MUA services in the digital era is now easy, with many choices on social media such as Instagram, which allows searches based on domicile, price, characteristics or quality. This research aims to analyze the personal branding of freelance MUAs in Pekanbaru via Instagram, using Montoya's personal branding theory with eight indicators ...
null Suci Shinta Lestari, null Mutia Farina   +1 more
openaire   +1 more source

The Visual Art Critic: A Survey of Art Critics at General Interest News Publications in America [PDF]

, 2002
Examines whether art critics provide sufficient exposure for artists and art institutions, given the recent dynamic growth in the visual arts over the past two ...
Andras Szanto
core  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Os media sociais nas estratégias de divulgação dos fotógrafos freelancers

, 2022
Social media today are as popular as traditional media. Their ease of use and accessibility have made them one of the preferred means for the dissemination of the most diverse situations. Social media marketing is currently part of the strategies of many companies.
openaire   +1 more source

From commercial marketing to electoral marketing: candidates’ attributes in the perception of Brazilian and American voters [PDF]

, 2017
This study investigates attributes that influence the vote in different socioeconomic contexts (Brazil/USA). Our results show an asymmetric effect of candidates’ attributes on voters’ decision.
Mainardes, Emerson, Quintino de Oliveira, Vinicius, Rondán Cataluña, Francisco Javier (Coordinador), Soares Monte-mor, Danilo   +3 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Entgrenzung als allgemeinerer Trend? Mobile Pflege und Arbeit in der Medien- und Kulturindustrie im Vergleich [PDF]

In der deutschsprachigen Arbeits- und Industriesoziologie wird derzeit eine intensive Debatte über die Entgrenzung von Erwerbsarbeit geführt. Hiermit ist gemeint, dass sich die industriegesellschaftlich etablierten Grenzen von Erwerbsarbeit verflüssigen ...
Henninger, Annette, Papouschek, Ulrike
core  

Property and the Construction of the Information Economy: A Neo-Polanyian Ontology [PDF]

, 2018
This chapter considers the changing roles and forms of information property within the political economy of informational capitalism. I begin with an overview of the principal methods used in law and in media and communications studies, respectively, to ...
Cohen, Julie E.
core   +1 more source