Results 231 to 240 of about 2,807,409 (305)

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

How digital twin technology revitalizes exhibits and enhances visitors' appreciation for ceramic collections in online museum tours. [PDF]

Sci Rep
Wang X, Liu Y, Wang W.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Expectation vs. reality: How stereotypes and expectation disconfirmation affect job evaluations in online labor markets. [PDF]

PLoS One
Tran Nhat D, Teubner T.
europepmc   +1 more source

Prevalence, socio-economic, and associated risk factors of oral cavity parasites in children with intellectual disability from Lorestan province, Iran. [PDF]

Front Cell Infect Microbiol
Selahbarzin B, Mahmoudvand H, Khalaf AK, Kooshki F, Farhadi F, Baharvand P.   +5 more
europepmc   +1 more source

Patients' Perspectives on Participation in an Effectiveness Study on Footwear Modification for the First Metatarsophalangeal Joint Osteoarthritis: A Qualitative Study. [PDF]

J Foot Ankle Res
Braam C, Kloprogge S, Schiphof D, van Meurs JBJ, Bierma-Zeinstra SMA, van Middelkoop M.   +5 more
europepmc   +1 more source

Factors influencing digital media designers' subscription to premium versions of AI drawing tools through a mixed methods study. [PDF]

Sci Rep
Hu L, Chen M, Ding N.
europepmc   +1 more source

From perceived risk to action: an individual-level study of how self-determination and new media shape public emergency rescue participation in China. [PDF]

Front Psychol
Zhang R.
europepmc   +1 more source

Resilience Development Among Adult Patients With De Novo Acute Leukemia: A Qualitative Study. [PDF]

Cancer Med
Li D, Li J, He X, Zhang M.
europepmc   +1 more source

PENGEMBANGAN SISTEM PENGGAJIAN YANG TERINTEGRASI DENGAN APLIKASI ARSIP SURAT BERBASIS WEB UNTUK PARA STAF FREELANCER DI CV LOKA MEDIA

Jurnal Informatika Dan Tekonologi Komputer (JITEK), 2023
Database Management is the main job that is part of the development of Information and Communication Technology. Along with the very rapid development of the world of Information and Communication Technology, the data and transaction management system has also experienced developments in its management.
null Dion Fahrul, null Henri Septanto
openaire   +2 more sources