Results 61 to 70 of about 2,807,409 (305)

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Multiplication des statuts précaires et (dé)structuration de l’espace professionnel

open access: yesSur le Journalisme, 2013
Cet article vise à interroger les formes d’encadrement du marché du travail du journalisme, la diversification des statuts d’emploi qui y ont cours et ses effets sur l’espace professionnel.
Cégolène Frisque
doaj  

The Brighton Fuse 2. Freelancers in the creative digital IT economy [PDF]

open access: yes, 2015
No description ...
Camerani, Roberto   +5 more
core   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Entgrenzung als allgemeinerer Trend? Mobile Pflege und Arbeit in der Medien- und Kulturindustrie im Vergleich [PDF]

open access: yes, 2005
In der deutschsprachigen Arbeits- und Industriesoziologie wird derzeit eine intensive Debatte über die Entgrenzung von Erwerbsarbeit geführt. Hiermit ist gemeint, dass sich die industriegesellschaftlich etablierten Grenzen von Erwerbsarbeit verflüssigen ...
Henninger, Annette, Papouschek, Ulrike
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Drifting Apart? European Journalists and Their Audiences [PDF]

open access: yes, 2008
How do the current technological changes and socio-political developments impact on the relationship between European journalists and their audiences?
Metykova, Monika
core   +2 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The Dark Side of Micro-Task Marketplaces: Characterizing Fiverr and Automatically Detecting Crowdturfing [PDF]

open access: yes, 2014
As human computation on crowdsourcing systems has become popular and powerful for performing tasks, malicious users have started misusing these systems by posting malicious tasks, propagating manipulated contents, and targeting popular web services such ...
Ge, Hancheng, Lee, Kyumin, Webb, Steve
core   +2 more sources

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