Results 91 to 100 of about 25,413,134 (267)

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Routledge Companion to British Media History

open access: yes, 2017
The Routledge Companion to British Media History provides a comprehensive exploration of how different media have evolved within social, regional and national contexts.

core  

The translation of biblion and biblos in the light of oral and scribal practice

open access: yesIn die Skriflig, 2016
The Bible was composed both by way of oral tradition and by scribal activity. Various descriptions exist of the development and relationship of the dominant forms of orality and scribal tradition throughout the history of media culture.
Jacobus A. Naudé   +1 more
doaj   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

The Study of Media Audiences

open access: yes, 2010
The aim of this one semester course is to provide an introductory guide to important theoretical and methodological concerns that have influenced audience studies alongside some of the seminal work on the persuasive power of media.
Department of Media and Communications
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Exploring U.S. History

open access: yes, 2004
The WARC file must be opened using a program like Webrecorder.io. The ZIP contains a static version of the website.These modules, designed for George Mason University's U.S.
Center for History and New Media
core   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Mass Media in a Changing World : History, Industry, Controversy

open access: yes, 2012
Mass Media in a Changing World introduces students to the world of media through a unique structure that makes the material easily intelligible and meaningful to their lives.
Rodman, George
core  

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