Results 121 to 130 of about 25,413,134 (267)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
, 2012 Producer, translator, subtitlerOver the last decade, Indigenous peoples and new social movements have produced the most profound and democratic transformation in the history of Latin America - the southern part of what Indigenous peoples call Abya Yala ...
Lehman, K
core
Craniofacial shape in children with and without a positive otitis media history. [PDF]
Int J Pediatr Otorhinolaryngol, 2016 Gremba AP +3 more
europepmc +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Ohio Historical Society Communication Exhibit photograph
, 1970 This photograph documents visitors to the Ohio Historical Society's exhibit on communication. The exhibit was one of the first to open in the new Ohio History Center in 1970. The photograph measures 9.5" x 7.5" (24.13 x 19.05 cm). Founded in 1885, the
Ohio History Connection
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
, 2008 This program is an excellent survey of the history of mass media. Academic and industry experts discuss the invention and impact of the printing press, telegraph, and telephone, all of which have allowed information to be easily transmitted over great ...
core
Digital Campus Podcast - Episode 55 – Social History
, 2010 Originally published by the Center for History and New Media through the Digital Campus podcast (http://digitalcampus.tv). This work is licensed under a Creative Commons Attribution 3.0 United States License (http://creativecommons.org/licenses/by/3.0/us/
Center for History and New Media
core +1 more source