Results 61 to 70 of about 3,143,128 (262)

The Future of Civil War History

open access: yes, 2016
In March 2013, hundreds of academics, preservationists, consultants, historical interpreters, museum professionals, living historians, students, K-12 teachers, and new media specialists gathered in Gettysburg, Pennsylvania to assess the state and ...
Broomall, James J.   +2 more
core   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Intro to the Zotero API

open access: yesThe Programming Historian, 2013
In this lesson, you’ll learn how to use python with the Zotero API to interact with your Zotero library. The Zotero API is a powerful interface that would allow you to build a complete Zotero client from scratch if you so desired.
Amanda Morton
doaj  

A Rule Set for the Future [PDF]

open access: yes, 2008
This volume, Digital Young, Innovation, and the Unexpected, identifies core issues concerning how young people's use of digital media may lead to various innovations and unexpected outcomes.
Tara McPherson
core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Creating New Items in Zotero

open access: yesThe Programming Historian, 2013
In Intro to the Zotero API, you learned a little bit about Zotero; now you can access some of its functions using Python scripts. In this lesson, you will create a new item in a Zotero library and add some basic metadata such as title and date.
Amanda Morton
doaj  

L’information internationale dans le quotidien La Presse au tournant du xxe siècle

open access: yesCommunication, 2011
Through a content analysis of the Quebec daily La Presse over a 30-year period, the author finds that the development of “new journalism,” at the turn of the 20th century, has reduced the newspaper’s front page coverage of international news. “Proximity”
Judith Dubois
doaj   +1 more source

Communication and the Knowable Community [PDF]

open access: yes, 2008
This essay draws on Raymond Williams\u27s concept of a knowable community in an effort to understand the myriad of connections that exist between individuals and society.
Brennen, Bonnie
core   +1 more source

Shifting new media: from content to consultancy, from heterarchy to hierarchy [PDF]

open access: yes, 2002
This is a detailed case history of one of London’s iconic new media companies, AMX Studios. Some of the changes in this firm, we assume, are not untypical for other firms in this sector. Particularly we want to draw attention to two transformations.
Andreas Wittel   +21 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

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