Results 151 to 160 of about 4,032,503 (309)
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Photothermal effects of gold nanorods in aqueous solution and gel media: Influence of particle size and excitation wavelength. [PDF]
IET Nanobiotechnol, 2023 Mbalaha ZS, Birch DJS, Chen Y.
europepmc +1 more source
Social media research: influencing the influencers
, 2012 One of the central concepts in marketing theory is the idea that some individuals are more\ud influential than others, and that these influencers play a central role in driving adoption of\ud new products and services. From a customer service perspective, when these influencers\ud are dissatisfied, they are able to drive disproportionally large numbers
Nunan, Dan, Cook, Alessia
openaire
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Perspectives on Terrorism, 2013 The media has played an important role in the ‘Global War on Terror’, and has received significant scholarly attention as a result. However, the way in which different media represent and construct notions of success and failure has been less
Sarah V. Marsden
doaj
Predicting Fact-Checking Health Information Before Sharing Among People with Different Levels of Altruism: Based on the Influence of Presumed Media Influence. [PDF]
Psychol Res Behav Manag, 2023 Wu Y.
europepmc +1 more source
, 2019 Influencer Marketing has become predominantly centered around social media. By connecting directly and organically through the showcase of social media influencers to their target markets, brands are able to achieve better results. Thus, more than ever, brands must know how to maximize the investment made when partnering with influencers.
openaire +1 more source
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Molecular Oncology, EarlyView.Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Digital Media Influence on Adolescents' Behavior during the COVID-19 Pandemic: Self-Intravenous Injection of Lactobacilli Drinking Yogurt. [PDF]
Children (Basel), 2022 Koh E, Choi I, Choi SA, Kang YJ, Cho HJ.
europepmc +1 more source