Results 61 to 70 of about 17,815,458 (309)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Control Dust on Gravel Roads with Soil Stabilization Innovations Polymers
, 2018 Now control dust on gravel roads with Soil Stabilization Innovations Polymers. Many government studies have proved that SSI polymers, when applied on gravel or dirt roads, produce more efficient results over the traditional methods.
soil stabilization innovations +1 more
core +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Making (Sense of) Media Innovations
, 2018 Media innovation is all around us in the form of new genres, new products, andnew platforms. But how can we understand these innovations? This chapter providesa theoretical exploration of the concept of media innovation and presentsthree steps to analyse
Krumsvik, A.H. +3 more
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Agents of Media Innovations: Actors, Actants, and Audiences
, 2014 In the contemporary media environment, media managers have been forced to reassess everything from editorial workflows to business models to technological platforms.
Lewis, Seth C., Westlund, Oscar,
core
The Media Welfare State: Nordic Media in the Digital Era [PDF]
, 2014 A dynamic examination of the media industry in the Nordic countries during the transition to today's digital ...
Hallvard Moe +7 more
core +1 more source
Framing the Schemata: Western Media Coverage of African Technological Innovations
Journalism and MediaThis study examines the framing of African technological innovations in Western media over the past two decades (2003–2023), focusing on four case studies: M-Pesa, LifeBank, FarmDrive, and NigeriaSat-1. Using a qualitative research design that integrates
Gregory Gondwe
doaj +1 more source
Expressive ways of creating new nominations in social networks (on the example of the Telegram social network) [PDF]
Известия Саратовского университета. Новая серия: Серия Филология, ЖурналистикаThe article analyzes expressive ways of creating new lexical units. The material consists of contexts of various contents extracted from the open resources of the Telegram messenger in the space of 2021–2023. Research methods and techniques include
Zamaldinov, Vladislav E.
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source