Results 241 to 250 of about 4,009,503 (294)

Depletion of the RNA‐Editing Enzyme ADAR1 Invigorates the Antitumor Immunity of NK Cells

Advanced Science, EarlyView.
ADAR1 is upregulated in NK cells from melanoma patients, impairing their function. Its loss enhances NK cell tumor infiltration and cytotoxicity in vitro and in vivo. Mechanistically, ADAR1 deficiency destabilizes CD38 mRNA to reduce its expression, thereby increasing NK cell mobility and killing, which nominates it as a therapeutic target for NK cell ...
Shuhan Chen, Di Lu, Rukang Liang, Weikeng Tan, Erming Zhao, Sihuang Wu, Xintong Li, Yulong Song, Miaojian Wan, Xiaoyuan Xie, Qi Zhang, Qiuli Liu   +11 more
wiley   +1 more source

Altmetric Activity and Scientific Integrity: A Retraction Analysis of PubMed-Indexed Social Media-Related Publications. [PDF]

J Korean Med Sci
Mukhamediyarov M, Zimba O, Yessirkepov M, Kocyigit BF.   +3 more
europepmc   +1 more source

Hypofractionated Radiotherapy Induces ISG15+MHC‐I+ Neutrophils to Augment Anti‐Tumor Immunity and Prime Immune Checkpoint Blockade Responses in Rectal Cancer

Advanced Science, EarlyView.
ABSTRACT Our previous clinical trials had demonstrated that neoadjuvant hypofractionated radiotherapy (HFRT) combined with immunotherapy yields promising clinical outcomes in locally advanced rectal cancer (LARC). However, this combined modality benefits only a subset of patients, highlighting the need to uncover the mechanisms underlying how ...
Lichao Liu, Haihong Wang, Mingjie Li, Qian Xu, Linlin Zheng, Chaoqun Han, Zhenwei Zou, Jinghua Ren, Xiaorong Dong, Peng Zhang, Kaixiong Tao, Zhenyu Lin, Tao Zhang   +12 more
wiley   +1 more source

"Play as a Nazi prison guard": childhood and adolescent exposure to online extremist materials in online gaming environments. [PDF]

Front Psychol
Hutchinson J, Gheorghe RM, Yuzva Clement D, Bell K, Kellum L, Rana M, Shuttleworth A, Scott-Smith S.   +7 more
europepmc   +1 more source

Coordination of Cyanobacterial Nitrate Assimilation and Photosynthesis by a Novel PsbO‐Interacting Protein PirN

Advanced Science, EarlyView.
PirN was identified as a previously uncharacterized PsbO‐interacting protein specifically induced in nitrate‐grown cyanobacteria. Loss of PirN leads to coordinated downregulation of PsbO and the nitrate reductase NarB, causing decreased PSII activity and impaired growth under nitrate conditions. Complementation with either PsbO or NarB largely restores
Chengcheng Huang, Zhen Xiao, Haitao Ge, Gaojie Wang, Jinghui Dong, Yan Wang, Hang Yang, Xing Wang, Hui Gao, Zhongshu Wang, Huanling Yang, Yuanya Zhang, Xiahe Huang, Wu Xu, Weimin Ma, Wenqiang Yang, Yingchun Wang   +16 more
wiley   +1 more source

Quality Analysis of YouTube and Facebook Videos for Glaucoma Treatment Options. [PDF]

Clin Ophthalmol
Sarrafpour S, Maheshwari A, Lee JH, Young BK, Liu J, Teng CC.   +5 more
europepmc   +1 more source

The Stanford Brainstorm Social Media Safety Plan (SMS): Introducing a New Tool. [PDF]

JMIR Ment Health
Djordjevic D, Vasan N.
europepmc   +1 more source

Exploring the associations between social media engagement and patient-centered communication among chronic disease patients: The mediating roles of information application and self-efficacy. [PDF]

Digit Health
Jiao Z, Yu X.
europepmc   +1 more source

Risky online self-disclosure in adolescents: a meta-analytic review of predictors and outcomes. [PDF]

Front Psychol
Sun J, Ghazali AHA, Abdul RSN.
europepmc   +1 more source

Prevalence and Associated Risk Factors of Suicidal Tendencies Among Bangladeshi Public University Students: A Mixed-Methods Exploration. [PDF]

Health Sci Rep
Uzzal NI, Mamun MA, Rashid MM, Kalam A.
europepmc   +1 more source