Results 151 to 160 of about 26,040,906 (290)
Innate Immunocompetent hiPSC‐Derived Neurospheroids Capture Early CNS Responses to rAAV
Advanced Science, EarlyView.Knowledge of human CNS immune responses to AAV‐based gene therapies remains limited due to the lack of immune‐competent human models. Here, a hiPSC‐derived 3D neuroimmune platform integrating neurospheroids and microglia is established using stirred‐tank bioreactors.
Catarina M. Gomes +14 more
wiley +1 more source
Advanced Science, EarlyView.Mitochondrial SLC25A46 is upregulated in ovarian cancer (OC) and correlates with poor prognosis. SLC25A46 stabilizes CACT to activate fatty acid oxidation, increasing ATP and NADPH production to drive cell proliferation and ferroptosis evasion. SLC25A46 silencing sensitizes OC cells to ferroptosis and carboplatin, offering a promising therapeutic ...
Yunge Gao +9 more
wiley +1 more source
Percepções de interatividade e tecnologia no processo de tutoria do FGV Online
, 2012 This paper aims to present and discuss the interactivity and technology in the process of mentoring in the Distance Learning Program Online FGV, focusing the discussion on the impacts of this process in the construction of students' knowledge.
Amaral, Rita
core
Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices
Advanced Science, EarlyView.Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen +9 more
wiley +1 more source
Dynamic Regulation of Endogenous Transcription Factor Hubs at Single‐Molecule Resolution
Advanced Science, EarlyView.This study combines single‐molecule microscopy and genome editing to characterize the dynamic behaviors of endogenous oncofusion transcription factor EWS::FLI1 in Ewing sarcoma cells. EWS::FLI1 forms neomorphic hubs that dynamically assemble and dissolve. The hubs are regulated during mitosis, by RNA, and by specific chemicals.
Shawn Yoshida +4 more
wiley +1 more source
Appearance-related social media behavior and eating disorder pathology: evidence from the german social media appearance preoccupation scale in nonclinical and clinical samples. [PDF]
J Eat DisordBrand S +4 more
europepmc +1 more source
Children worldwide gain benefits, face risks online
, 2016 A majority of children say they learn something new online at least every week, but large numbers still face risks online, according to the Global Kids Online Research Synthesis Report 2015 – 2016 produced by the UNICEF Office of Research – Innocenti and
Global Kids Online
core
College Students' Social Media Use and Digital Well-Being: The Chain Mediating Roles of Social Capital and Digital Trust. [PDF]
Psychol Res Behav ManagZhang H, Chen L, Deng W.
europepmc +1 more source
Advanced Science, EarlyView.Interpretable machine learning reveals how composition and processing govern the formation and microstructural burden of Fe‐rich intermetallic compounds in recycled Al–Si–Fe–Mn alloys. By separating morphology selection from morphology‐conditioned burden partitioning, this framework shows that identical Fe contents can yield different intermetallic ...
Jaemin Wang +2 more
wiley +1 more source