Results 51 to 60 of about 322,726 (301)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Mapping Time-Varying Accessibility and Territorial Cohesion With Time-Distorted Maps

open access: yesIEEE Access, 2019
Human societies have radically changed from the second half of the 20th century. Urban areas are increasingly concentrating more people and economic activities.
Jose Balsa-Barreiro   +3 more
doaj   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

open access: yesFEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner   +7 more
wiley   +1 more source

Effects of Health Messages on Knowledge, Satisfaction, and Anxiety of Patients’ Companions Referring to Tehran Heart Center [PDF]

open access: yesJournal of Education and Community Health, 2018
Background and Objectives: One of the most important concerns of health care professionals is information. This study was conducted with the aim of investigating the effects of health-message broadcast via the closed-circuit television (CCTV) system of ...
Monir Sadat Akhlaghi   +2 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Diversity and public engagement in planning: A case study of Chinese migrants in Christchurch

open access: yes, 2019
Aotearoa New Zealand’s population has grown rapidly from 3.85 million in 2000, to 5 million in 2020. Ethnic diversity has consequently increased. Territorial Authorities (TAs) undertaking statutory consultation and wider public engagement processes need ...
Wang, Sai   +2 more
core   +1 more source

The varied restorative values of campus landscapes to students’ well-being: evidence from a Chinese University

open access: yesBMC Public Health
Background The literature on therapeutic landscapes highlights that the university campus landscape has restorative effects on students. This deserves more scholarly attention since mental health has become an important issue among university students ...
Xuanyi Nie   +4 more
doaj   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

Analysis of Urban Mobility on a University Campus: Greenhouse Gas Emissions at the Brusque University Centre (UNIFEBE), Brazil

open access: yesProceedings
Climate change is one of the greatest challenges of the 21st century, with global warming, driven by greenhouse gas (GHG) emissions, at its core [...]
Karol Diego Carminatti Baumgärtner   +4 more
doaj   +1 more source

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