Results 51 to 60 of about 9,740,699 (341)
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Media Policy and the Party Manifestos – Some Ideas [PDF]
, 2014 Now is the time in the political cycle when the main parties are writing their manifestos. So what could go in the media policy sections? The Media Policy Project does not have a partisan position.
Media Policy Project Blog,
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
New Research: Media, the Internet, and Security Post-Snowden [PDF]
, 2013 PEN American Center’s report this week, “Chilling Effects” shows that growing surveillance has driven some American writers to censor their work. The findings from the survey of over 500 PEN writers, conducted in October 2013, demonstrate that writers ...
Media Policy Project Blog,
core
Sustainability, 2020 Having geographical proximity and a high volume of trade with China, the first country to record an outbreak of the new Coronavirus disease (COVID-19), Vietnam was expected to have a high risk of transmission.
Viet-Phuong La +10 more
semanticscholar +1 more source
Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Open Linguistics, 2017 The poststructuralist turn has been widely acknowledged in contemporary applied and sociolinguistics (Rampton 2006, Blommaert 2010). While for many this paradigmatic shift has been a welcome challenge to segregationalist approaches (Mühlhäusler 1996 ...
Kelly-Holmes Helen, Atkinson David
doaj +1 more source
A Progressive Licence Fee for a Progressive Era [PDF]
, 2014 As the Parliamentary Select Committee on the Future of the BBC continues to hear evidence on what shape the Royal Charter should take when it’s renewed in 2016 with a session this past Tuesday, Ronan Costello, an MSc student at the LSE suggests making ...
Media Policy Blog Team,
core
Arthritis Care &Research, EarlyView.Objective Sjögren's disease is an autoimmune disorder that can impact multiple organ systems, including the peripheral nervous system (PNS). PNS manifestations, which can exist concurrently, include mononeuropathies, polyneuropathies, and autonomic nervous system neuropathies.
Anahita Deboo +88 more
wiley +1 more source
Essential research in the field of theoretical concepts of media policy [PDF]
مدیریت دولتی, 2015 Media policy is the major strategies that guide the media in achieving the specific objectives. Since the field of media policy area in the country is unknown, purpose of this study is carried out theoretical research in the field of media policy and ...
Taher Roshandel Arbatani
doaj +1 more source