Results 131 to 140 of about 594,164 (165)

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

open access: yesFEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu   +6 more
wiley   +1 more source

Enhanced discovery of bacterial laccase‐like multicopper oxidase through computer simulation and metagenomic analysis of industrial wastewater

open access: yesFEBS Open Bio, EarlyView.
We obtained potential bacterial laccase‐like multicopper oxidase (LMCO) sequences through metagenomic sequencing. All sequences exhibited significant differences from known LMCOs in databases. To select the most promising candidates, we performed structure prediction and molecular docking using alphafold2, metal3d and rosetta.
Ting Cui   +5 more
wiley   +1 more source

Comparative study of adenosine 3′‐pyrophosphokinase domains of MuF polymorphic toxins

open access: yesFEBS Open Bio, EarlyView.
With the ultimate goal of understanding the association of toxin‐immunity modules to temperate phages, we characterized toxins from three prophages and examined cross‐protection from immunity proteins. The toxins exhibit adenosine 3′‐pyrophosphokinase activity and are toxic in Escherichia coli.
Eloïse M. Paulet   +6 more
wiley   +1 more source

KCS1 and VIP1, the genes encoding yeast phosphoinositol pyrophosphate synthases, are required for Ca2+‐mediated response to dimethylsulfoxide (DMSO)

open access: yesFEBS Open Bio, EarlyView.
Ca2+‐mediated response to DMSO was investigated in Saccharomyces cerevisiae cells expressing Ca2+‐dependent aequorin. Cell exposure to DMSO induced a cytosolic Ca2+ wave dependent on the integrity of the Cch1/Mid1 channel. Deletion of KCS1 or VIP1 genes encoding the phosphoinositol pyrophosphate (PP‐IP) synthases suppressed the DMSO‐induced Ca2 ...
Larisa Ioana Gogianu   +4 more
wiley   +1 more source
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Representations of childhood in the media

2013
Childhood is, and has always been, an unstable concept, variously interpreted and represented according to historical, social, cultural, political and economic contexts as Philippe Aries shows in his ground-breaking work, Centuries of Childhood (1962). Aries’ work is regarded as a fundamental text informing study on representations of childhood, as it ...
Giselle Rampaul, Debbie Olson
openaire   +2 more sources

Youth street groups and media representations

2023
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No ...
Masanet, Maria-Jose   +5 more
openaire   +1 more source

Media Representations of Sexting

2015
In recent years, sexting as a concept has gained traction in popular and media discourse, becoming one of a suite of issues canvassed by the media that come under the umbrella of cyberporn, cyberbullying and other technologically facilitated ‘harms’. While a growing body of work has begun to emerge about the experiences, understandings and perceptions ...
Thomas Crofts   +3 more
openaire   +2 more sources

KNOWLEDGE-BASED REPRESENTATION OF 3D MEDIA

International Journal of Software Engineering and Knowledge Engineering, 2010
In recent years, 3D media have become more and more widespread and have been made available in numerous online repositories. A systematic and formal approach for representing and organizing shape-related information is needed to share 3D media, to communicate the knowledge associated to shape modeling processes and to facilitate its reuse in useful ...
G Vasilakis   +7 more
openaire   +4 more sources

Media and the representation of Others

International Social Science Journal, 2010
This article criticises the role the mass media has played in constructing an idea of the Other, that is, people outside the national mainstream or other nationalities. It explains how the media promote or hinder a positive outlook on cultural diversity. Based on a review of the scholarly debate on media representations of Others, it identifies current
openaire   +2 more sources

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