Results 51 to 60 of about 487,519 (267)

ANALYSIS OF MEDIA CONSUMPTION TRENDS IN UKRAINE FOR THE YEARS 2022 – 2024

open access: yesІнтегровані комунікації
The article analyses media consumption trends in Ukraine in 2022-2024, a hugely difficult time for the nation during the full-scale invasion of Russia into Ukraine.
Kateryna Balabanova
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Pragma-communicative analysis of evaluation as a fundamental instrument of forming intentional intersubject dialogue

open access: yesStudia Humanitatis, 2018
The article carries out a complex pragma-communicative analysis of the category of evaluation as a predominant component in the formation of intentional intersubjective communication. At the beginning the authors provide the definitional analysis of the “
Bagiyan Alexander Yurievich   +1 more
doaj  

INTERMEDIALITY, INTERTEXTUALITY, INTERDISCURSIVITY: CORRELATION OF NOTIONS IN THE LIGHT OF MASSMEDIA DISCOURSE STUDIES

open access: yesГуманитарные и юридические исследования, 2021
The article studies the key notions conveying the forms and mechanisms of interaction in linguocultural space, namely intermediality, intertextuality and interdiscursivity. Dynamic processes connected with the extension of media in all areas of life, the
T. Marchenko
doaj  

YouTube as a New Form of Mediatization

open access: yesВісник Київського національного університету культури і мистецтв. Серія: Аудіовізуальне мистецтво і виробництво, 2020
The purpose of this research is to analyze and generalize the features and techniques of the YouTube platform as a new form of mediatization. Research Methodology.
Kostiantyn Hrubych, Yelyzaveta Burkhan
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

The Arctic in the Post-Truth Era: Risks to International Security and Counteraction Scenarios

open access: yesАрктика и Север
The article examines the impact of the post-truth phenomenon on the perception of international securi-ty in the Arctic region. The main focus is on analyzing information distortions in the media resources of leading foreign mass media outlets (The New ...
Konstantin S. Zaikov   +1 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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