Results 91 to 100 of about 6,239,559 (301)

The Effects of Social Media Use on the Perceptions of Mental Illness Among College Students [PDF]

open access: yes, 2019
This study examined individuals’ use of and perceptions of social media networking sites (i.e. Facebook and Twitter) on their perceptions of mental illness.
Fisher, Brea
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

The Role of Linguistics Studies on the Political Debate [PDF]

open access: yes, 2019
The paper is to find out the linguistics role contribution towards the political debate event at the election party. The presidential debate\u27s primary purpose is to sponsor and produce debates for the United States presidential and vice-presidential ...
Collins, L. (Lee), Jisum, C. (Chang)
core  

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Teaching journalism and mass communication during the COVID-19 pandemic: Zambian lecturers’ experiences of the transition to online instruction

open access: yesDiscover Education
The global outbreak of the Corona Virus Disease (COVID-19) brought a myriad of challenges to higher education. At tertiary institutions worldwide, the closure of campuses and the migration to online instruction came as an unplanned consequence for ...
Carole Phiri-Chibbonta   +2 more
doaj   +1 more source

Diversity in Western Countries: Journalism Culture, Migration Integration Policy and Public Opinion

open access: yesMedia and Communication, 2019
Earlier research has shown that public opinion and policy lines on the topic of immigrant integration are interrelated. This article investigates a sample of 24 countries for which data are available in the Migrant Integration Policy Index (MIPEX), the ...
Stefan Mertens   +3 more
doaj   +1 more source

Studies of new media radiation induced laser [PDF]

open access: yes
Various lasants were investigated especially, 2-iodohepafluoropropane (i-C3F7I) for the direct solar pumped lasers. Optical pumping of iodine laser was achieved using a small flashlamp.
Han, K. S.   +4 more
core   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Communicating on Twitter for Charity: Understanding the Wall of Kindness Initiative in Afghanistan, Iran, and Pakistan

open access: yesInternational Journal of Communication, 2018
This study highlights the important role of social media for charity through an analysis of tweets about the Wall of Kindness charity initiative in Afghanistan, Iran, and Pakistan. Using both quantitative and qualitative methods, we employ a theoretical
M. Laeeq Khan, Zulfia Zaher, Bowen Gao
doaj   +2 more sources

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