Results 91 to 100 of about 50,670,518 (386)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

open access: yesFEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang   +9 more
wiley   +1 more source

Image networks and practice analysis of larger data corpora. An approach to cluster and recontextualize visual practice in social media

open access: yesStudies in Communication Sciences
This paper reports a methodological exploration combining image network analysis and standardized practice analysis on social media data. Through applying the open source software Memespector to access the Clarifai API, the potential of an easy-at-hand ...
Wolfgang Reißmann   +2 more
doaj   +1 more source

“We Have to Move Quickly to Cement This Willingness for Change”: News Narratives About Declarations of Racism as a Public Health Crisis, 2019–2021

open access: yesHealth Equity
Objective: To understand how declarations of racism as a public health crisis were portrayed in the news from 2019 to 2021. Methods: We assessed a national sample of articles (n = 127) to see how declarations of racism as a public health crisis were ...
Hina Mahmood   +5 more
doaj   +1 more source

Social media as a data gathering tool for international business qualitative research: opportunities and challenges [PDF]

open access: yes, 2018
Lusophone African (LA) multinational enterprises (MNEs) are becoming a significant pan-African and global economic force regarding their international presence and influence.
Cornelius Smith, Erika   +1 more
core   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

How Swiss is Swiss television? Analysing structural and content references in SRG SSR television programmes

open access: yesStudies in Communication Sciences, 2022
No Billag – in Switzerland, the debate about the necessity and financial viability of public broadcasting has been sparked anew. Closely linked are questions about the public value of the SRG SSR and how much of Switzerland is actually portrayed on Swiss
Eva Spittka   +3 more
doaj   +1 more source

Jim Udden, Professor of Cinema & Media Studies

open access: yes, 2018
In this Next Page column, we ask Jim Udden, Professor of Cinema & Media Studies, to talk books instead of films. Find out which authors make him laugh, his go-to source for reading about new books, and what he is planning to read as soon as his end-of ...
Musselman Library,, Udden, James N.
core  

Embodied memory and curatorship in children’s digital video production [PDF]

open access: yes, 2010
Digital video production in schools is often theorised, researched and written about in two ways: either as a part of media studies practice or as a technological innovation, bringing new, “creative”, digital tools into the curriculum.
Potter, John
core   +2 more sources

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

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