Results 301 to 310 of about 50,853,159 (386)

From stress to screen: family factors on the path to problematic media use in children aged 4-11. [PDF]

Front Psychol
Yayla İE, Makas S, Yıldırım S, Dombak K, Çelik E.   +4 more
europepmc   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Response to "Co-Culture Shock" by Behan & Mittelman: Co-culture shock? Let's integrate! [PDF]

Cell Death Discov
Zinngrebe J, Fischer-Posovszky P.
europepmc   +1 more source

An investigation of the relation between online and offline violence: methodological and theoretical considerations. [PDF]

Front Psychol
Molenaar MG, Weerman FM, Defoe IN.
europepmc   +1 more source

Modeling neurovascular dysfunction in Alzheimer's disease using an isogenic brain-chip model. [PDF]

Fluids Barriers CNS
Shen AN, Matazel KS, Gill WD, Ewart L, Daughters RS, Rosas-Hernandez H.   +5 more
europepmc   +1 more source

The Impact of Social Media on Adolescents' Eating and Sleeping Habits: A Systematic Review and Meta-Analysis. [PDF]

Healthcare (Basel)
Cal-Herrera A, Corbella-González A, Climent-Llinares S, Fernández-Rodríguez OI.   +3 more
europepmc   +1 more source

Social Media Use Among Parents and Caregivers of Children With Rare Genetic Diseases: Scoping Review.

J Med Internet Res
Davis C, Bogaert L, Powell J, Low K.
europepmc   +1 more source

Enhancing media literacy to combat information fragmentation in digital short video platforms: a cross-sectional study. [PDF]

Sci Rep
Yu T, Wei C, Na M, Alam SS.
europepmc   +1 more source

Improving the communication of uncertainty in food safety on social media: a content analysis of aspartame risk messages. [PDF]

Front Public Health
Chen Y, Luo S, Xu L, Tan M.
europepmc   +1 more source