Results 61 to 70 of about 48,502,445 (376)

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Role of Epidemiological Studies in Disease Prevention [PDF]

, 2019
Today's society is full of disease that are of different natures including genetic, infectious and metabolic etc. Every disease has its own mechanisms of affecting humans and different prevention mechanisms as per disease nature.
Akthar, M. S. (Muhammad)
core  

Intercultural New Media Studies: The Next Frontier in intercultural Communication [PDF]

, 2012
New media (ICT\u27s) are transforming communication across cultures. Despite this revolution in cross cultural contact, communication researchers have largely ignored the impact of new media on intercultural communication.
Buber M, Camir FL, Casmir FL, Casmir FL, Chen GM, Chen GM, Chia-I H, Chun DM, Collier MJ, Colomb G, Croucher SM, Gadamer HG, Guéguen N, Habermas J, Hichang C, Hopkins L, Hu SLY, Jones S, Khan M, Kim YY, Kim YY, Koc M, Ling R, Ma R, Meagher ML, Robert Shuter, Shuter R, Singh C, Starosta WJ, Tajfel H, Turkle S, Yoon R   +31 more
core   +2 more sources

Digital In- and Exclusion in Everyday Life: Practices and Literacies Across the Lifespan

Media and Communication
In this thematic issue of Media and Communication titled Practices of Digital In- and Exclusion in Everyday Life, we bring together insights from around the world to offer a diverse set of perspectives on digital practices and digital literacies across ...
Marcel Broersma, Joëlle Swart, Denise Mensonides, Alex Smit, Maud Rebergen   +4 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source

Ecological Studies on Nepenthes at Barito Ulu, Central Kalimantan, Indonesia [PDF]

, 2008
Ecological studies on the Nepenthes species at Barito Ulu, Central Kalimantan, Indonesia were conducted between August 2005 and September 2006. Surveys and two small plot inventories were used to determine the diversity and population of Nepenthes at the
Mansur, M. (Muhammad)
core  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Alien nation: contemporary art and black Britain [PDF]

, 2011
About the book: This fascinating text introduces readers to postcolonial theory using the context of British media culture in ethnic minority communities to explain key ideas and debates.
Wainwright, Leon
core   +1 more source

Why “intergenerational feminist media studies”?

An Intergenerational Feminist Media Studies, 2016
Feminism and generation are live and ideologically freighted issues that are subject to a substantial amount of media engagement. The figure of the millennial and the baby boomer, for example, regularly circulate in mainstream media, often accompanied by
Alison Winch, J. Littler, J. Keller
semanticscholar   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source