Results 101 to 110 of about 76,371 (291)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Dependency Relations and Newspaper Readership
, 1993 Newspaper readership often has been studied with the aim of developing demographic profiles of readers. This paper considers the goals readers are pursuing and the importance of media system dependency relations in explaining the amount of time spent ...
Sandra J. Ball-Rokeach, William E. Loges
core +1 more source
Frontiers in PsychologyIntroductionAddressing the impact of problematic mobile phone use on sleep quality has become a topic of concern for researchers, but the underlying mechanisms and effective intervention strategies remain under explored.MethodsThe aim of this study was ...
Fen Xie, Mengyu Li
doaj +1 more source
Metaheuristic-driven optimization of ensemble deep learning model for image manipulation classification [PDF]
PeerJ Computer ScienceDetecting image manipulations, particularly in double Joint Photographic Experts Group (JPEG)-compressed images, remains a critical challenge in digital forensics due to the repetitive compression chain introduced by social media platforms.
Rukiye Karakis +3 more
doaj +2 more sources
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
BMC Public HealthBackground Older adults (> 55 years), in particular low-income older adults, have lower health literacy than the rest of the Canadian population. Lower health literacy is related to several negative health outcomes such as poor diabetes control and other
Pauneez Sadri +6 more
doaj +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
Specifying Functional Requirements Dependency in the REWiki [PDF]
, 2013 Most of the individual requirements cannot be treated in isolation. Requirements may affect each other in various ways. The dependency between requirements impacts a number of software development aspects and activities.
ZHANG, ZHANG
core
The Effects of Marketing Related Activities on Brand Equity through Facebook
Journal of Business and Social Review in Emerging Economies, 2021 Purpose of the Study: The study aims to examine and analyze the effects of various marketing related activities on brand equity through Facebook. Methodology: An online survey was conducted for this empirical form of research.
Shahzad Khan Durrani +3 more
doaj
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source