Results 41 to 50 of about 20,723,232 (242)

The Impact of Social Media Addiction on Adolescent Mental Health in Ambon City, Indonesia

open access: yesBiology, Medicine & Natural Product Chemistry
The increasing prevalence of social media use among adolescents has raised concerns regarding its potential impact on mental health. This study investigated the relationship between social media addiction and adolescent mental health in Ambon, Indonesia.
Josephus Noya, Vernando Yanry Lameky
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

The stratification of media usage in Finland, 2007–2018: Signs of socio-political polarization?

open access: yes, 2020
Over the last 10–15 years, Western societies have faced two interrelated social changes: the digitalization of media and the increase in socio-political polarization.
Leguina, Adrian   +2 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Influencing Factors in the Depth-Usage of Social Media as the Business Platform by Student Entrepreneurs

open access: yesAMAR (Andalas Management Review), 2019
This paper examines factors that influence the depth-usage of social media as a business platform among student entrepreneurs by focusing analysis on the mediating effect of social media adoption.
Hafiz Rahman, Rahmad Hidayat
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Does social media usage matter? An analysis of online practices and digital media perceptions of communication practitioners in Europe [PDF]

open access: yes, 2014
A key aspect for understanding and explaining online communication is the micro level of communication practitioners’ social media usage and their general attitudes towards digital platforms.
Moreno, Angeles   +7 more
core   +1 more source

Examining How Digital Divides Shape Social Media Platform Preference and Usage in Climate-Vulnerable Coastal Bangladesh

open access: yesJournal of Social Sciences and Humanities
This study investigates the influence of demographic disparities on social media usage patterns among climate-vulnerable, resource-constrained coastal communities, based on Digital Divide Theory.
Imran Khan   +2 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

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