Results 71 to 80 of about 20,723,232 (242)

Social media driven mediatization of youth in BRICS

open access: yesRUDN Journal of Studies in Literature and Journalism
Over the years, social media has emerged as the largest source for global communication. In post-COVID-19 times and especially in the New Reality, social media consumption patterns have shifted significantly.
Zamaswazi P. Cele   +2 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Cross-Platform News Media Repertoires and Their Political Implications

open access: yesInternational Journal of Communication, 2021
With the expansion of news media platforms, news media usage patterns and their implications on civic and political engagement have become complex. To better understand these complexities, this study examines cross-platform news media repertoires and ...
Su Jung Kim, Lena-Maria Schwarze
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Physical and digital media usage patterns on interactive tabletop surfaces

open access: yes, 2010
Concurrent interaction with physical and digital media is ubiquitous in knowledge work. Although tabletop systems increasingly support activities involving both physical and digital media, patterns of use have not been systematically assessed. This paper
Mühlhäuser, Max   +8 more
core   +1 more source

Media Multitasking: An Exploratory Study on Students’ Multiple Media Uses and Behaviours in Karachi

open access: yesJournal of Mass Communication, 2019
The main objective of this research is to discover the media multitasking and multiple media use practices among youth of Karachi. The development and new patterns of usage of mass media technology have born a digital media generation who use multiple ...
Sabir Ahmed, Asmat Ara, Sanam Tajjamul
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Smartphone Usage Patterns and Sleep Behavior in Demographic Groups: Retrospective Observational Study

open access: yesJournal of Medical Internet Research
BackgroundAlthough previous studies have examined the relationship between smartphone usage and sleep disorders, research on demographic differences in smartphone usage and nocturnal smartphone inactivity patterns remains limited.
Ting Wang   +5 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

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