Results 81 to 90 of about 6,828,197 (312)

The Use of Connotative Meaning Derived From Darwis Tere Liye\u27s Quotes on Facebook [PDF]

open access: yes, 2015
The study deals with the use of connotative meaning especially inDarwisTereLiye\u27s quotes. In this study the researcher focuses on the three maintypes of connotative meaning namely positive connotative, negative connotativeand neutral connotative.
Muhammad Natsir, RizkaZulhaini and
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Dynamics of Sensemaking and Information Seeking in a Crisis Situation

open access: yesNordicom Review, 2016
The present article investigates two questions: What determines citizens’ use of different media to seek information in a crisis situation, and what influences their evaluation of the information found.
Vigsø Orla, Odén Tomas
doaj   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

The Use of Social Media by UK Local Resilience Forums [PDF]

open access: yes, 2014
The potential uses of social media in the field of emergency preparedness, resilience and response (EPRR) are varied and interesting. The UK government have produced guidance documents for its use in the UK EPRR field but evidence of use is poorly ...
Meaton, Julia, Stringer, Lisa
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

The Association between Use of Online Social Networks to Find Sex Partners and Sexually Transmitted Infection Diagnosis among Young Men Who Have Sex with Men and Transgender Women Living with HIV. [PDF]

open access: yes, 2019
We conducted a cross-sectional analysis of baseline data from the Adolescent Trials Network for HIV/AIDS Interventions to examine the association between the use of social media sites to find sex partners and recent diagnosis of sexually transmitted ...
Hightow-Weidman, Lisa   +4 more
core   +2 more sources

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Modifiable unhealthy lifestyle behaviours in subclinical manifestations of attention-deficit hyperactivity disorder: what are the first empirical results and putative clinical implications?

open access: yesBJPsych Open
Attention-deficit hyperactivity disorder (ADHD) is one of the most common mental disorders in adolescents, and a full syndrome diagnosis requires a combination of persistent symptoms. In a multicentre cross-sectional study from Italy using a non-clinical
Kristin Annawald, Thomas Meyer
doaj   +1 more source

Not so social media: Twitter use in the conference sector [PDF]

open access: yes, 2013
This research forms part of a larger project funded by Meeting Professionals International (MPI) focusing on the future of business events . In this paper we investigate the motivations for social media use within a professional event context.
Dixon, SJ, Wood, E
core  

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