Results 171 to 180 of about 103,424 (233)

AI in Mental Health: Transforming Diagnosis and Management of Depression and Anxiety. [PDF]

Health Sci Rep
Kambar T, Tariq S, Shahzad S, Sultan HS, Siddiqui AN, Shah FA, Khanani H, Khan A, Shah HH, Rauf SA, Zuberi MAW, Waseem R, Hussain MS, Haque MA.   +13 more
europepmc   +1 more source

Chemoselective Metabolomics via a Modular Reactivity‐Encoding Platform

Advanced Science, EarlyView.
Conventional LC–MS underrepresents numerous metabolites due to heterogeneous ionization efficiencies and matrix interference. Here, we introduce a modular reactivity‐encoding platform (MREP) comprising four alkyne‐tagged probes that selectively derivatize key functional groups, followed by unified click‐chemistry capture to eliminate matrix components ...
Xin Tao, Cang‐Man Zhang, Ru‐Jie Yang, Min Ren, Zhuo‐Ling Zhong, Kang‐Hui Wang, Rui‐Xue Hu, Jia‐Yue Liu, Jun‐Yi Zhou, Hou‐Kai Li, Jian‐Bo Wan   +10 more
wiley   +1 more source

Clinical artificial intelligence applications of vision-language foundation models. [PDF]

PLOS Digit Health
Thirunavukarasu AJ, Li S, Qin P, Nie D, Sanghera R, Lim E, Yu J, Zhang L.   +7 more
europepmc   +1 more source

LRG1 Drives Pathological Angiogenesis by Disrupting Neutrophil Mitochondrial Homeostasis in Bladder Cancer

Advanced Science, EarlyView.
In bladder cancer, LRG1 binds to ANXA2 to trigger mitochondrial ROS‐dependent NETosis. This pathogenic cascade actively uncouples endothelial‐mural cell interactions, driving profound vascular destabilization. Consequently, targeting the LRG1‐ANXA2 axis attenuates the neutrophil burden and induces structural vascular normalization, offering a powerful ...
Dongshan Chen, Cong Zhang, Song Xue, Yuan Zeng, Haochen Cui, Chenfei Wang, Jiayi Feng, Lei Yan, Yuanwei Zang   +8 more
wiley   +1 more source

Characterising 'Spree Bar': an examination of the popularity, marketing and composition of a vaping device with a nicotine analogue across multiple data streams. [PDF]

Tob Control
O'Connor RJ, Li D, Xie Z, Page MK, Felicione NJ, Schneller-Najm LM, Ye P, Raczyk A, Bansal-Travers M, Goniewicz ML.   +9 more
europepmc   +1 more source

Subversion of Atypical Mucin Traps by a Spore‐Coat Effector Blocks Cellular Immunity in Drosophila

Advanced Science, EarlyView.
While the entomopathogenic fungus Metarhizium robertsii can evade insect humoral immunity, its subversion of cellular defenses is still elusive. We identify Eac1 as a spore‐coat protein essential for infecting drosophilids by targeting atypical mucins (Sgf1 and Sgf2), which can entrap spores in a gel matrix and thereby facilitate hemocyte encapsulation.
Shiqin Li, Haimin Chen, Gangqi Fang, Dongxiang Wei, Hongyun Wu, Chen Chen, Song Hong, Chengshu Wang   +7 more
wiley   +1 more source

Towards an accessible, centralised, searchable database for AI courses in Europe: the Artificial Intelligence in Medical Imaging and Radiation Oncology Education (AIMIROE) project. [PDF]

Eur Radiol Exp
Decoster R, Erenstein H, Menzinga J, Cornacchione P, Cunha A, Dybeli E, Mekis N, McEntee M, Paalimäki-Paakki K, Precht H, Akinci D'Antonoli T, Cuocolo R, Huisman M, Klontzas ME, Kotter E, Pinto Dos Santos D, Ranschaert E, van Ooijen P, Stogiannos N, Malamateniou C.   +19 more
europepmc   +1 more source

Regulating Droplet Dynamics via Wormlike Micelle Networks: From Splash Suppression to Precise Confined Spreading

Advanced Science, EarlyView.
As displayed in Graphical Abstract image.tif, a molecular‐design strategy precisely tailors high‐speed droplet dynamics through programmed surfactant co‐assembly. The structural transition into an entangled wormlike micelle network completely suppresses stochastic splashing on fibrous substrates.
Shuling Liu, Beibei Xie, Xingyue Lou, Yu Deng, Lei Wang, Jiawei Li, Dongming Qi   +6 more
wiley   +1 more source

Tweets Surrounding Pharmaceutical Drug Brands With Top Direct-to-Consumer TV-Advertising Budgets: Social Media Listening Study. [PDF]

Online J Public Health Inform
Macias W, Navarro Castillo MB.
europepmc   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source