Results 171 to 180 of about 22,462 (202)

Modification of temporal pattern sensitivity for inputs from medial entorhinal cortex by lateral inputs in hippocampal granule cells. [PDF]

Cogn Neurodyn
Nakajima N, Kamijo T, Hayakawa H, Sugisaki E, Aihara T.   +4 more
europepmc   +1 more source

Microcircuits for spatial coding in the medial entorhinal cortex [PDF]

Physiological Reviews, 2022
The hippocampal formation is critically involved in learning and memory and contains a large proportion of neurons encoding aspects of the organism’s spatial surroundings. In the medial entorhinal cortex (MEC), this includes grid cells with their distinctive hexagonal firing fields as well as a host of other functionally defined cell types including ...
John Tukker, Richard Kempter, Michael Brecht   +2 more
exaly   +6 more sources

The medial entorhinal cortex encodes multisensory spatial information [PDF]

Cell Reports
Animals employ spatial information in multisensory modalities to navigate their natural environments. However, it is unclear whether the brain encodes such information in separate cognitive maps or integrates it all into a single, universal map. We address this question in the microcircuit of the medial entorhinal cortex (MEC), a cognitive map of space.
Yi Gu
exaly   +6 more sources

Object-vector coding in the medial entorhinal cortex [PDF]

Nature, 2019
The hippocampus and the medial entorhinal cortex are part of a brain system that maps self-location during navigation in the proximal environment1,2. In this system, correlations between neural firing and an animal's position or orientation are so evident that cell types have been given simple descriptive names, such as place cells3, grid cells4 ...
May-Britt Moser, Edvard Moser, Moser May-Britt   +2 more
exaly   +4 more sources

Multiple Running Speed Signals in Medial Entorhinal Cortex [PDF]

Neuron, 2016
Grid cells in medial entorhinal cortex (MEC) can be modeled using oscillatory interference or attractor dynamic mechanisms that perform path integration, a computation requiring information about running direction and speed. The two classes of computational models often use either an oscillatory frequency or a firing rate that increases as a function ...
James Hinman, Michael Hasselmo, Mark Brandon   +2 more
exaly   +3 more sources

Distance-tuned neurons drive specialized path integration calculations in medial entorhinal cortex [PDF]

Cell Reports, 2021
Malcolm Campbell, Surya Ganguli, Lisa Giocomo   +2 more
exaly   +2 more sources

Complementary Modular Microcircuits of the Rat Medial Entorhinal Cortex [PDF]

Frontiers in Systems Neuroscience, 2017
The parahippocampal region is organized into different areas, with the medial entorhinal cortex (MEC), presubiculum and parasubiculum prominent in spatial memory. Here, we also describe a region at the extremity of the MEC and bordering the subicular complex, the medial-most part of the entorhinal cortex.
Robert K Naumann, Saikat Ray, Michael Brecht   +2 more
exaly   +4 more sources

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Cellular properties of principal neurons in the rat entorhinal cortex. II. The medial entorhinal cortex

Hippocampus, 2011
AbstractPrincipal neurons in different medial entorhinal cortex (MEC) layers show variations in spatial modulation that stabilize between 15 and 30 days postnatally. These in vivo variations are likely due to differences in intrinsic membrane properties and integrative capacities of neurons.
Canto, C.B., Witter, M.P.
openaire   +2 more sources

A heart-like Na+ current in the medial entorhinal cortex

Neuron, 1993
Acutely dissociated neurons from the superficial layers of the medial entorhinal cortex of the rat were studied under voltage clamp using the whole-cell patch-clamp configuration. Neurons from the medial entorhinal cortex exhibit a tetrodotoxin (TTX)-resistant Na+ current (ITTX-R; IC50 approximately 146 nM), in addition to the normal TTX-sensitive Na ...
J A, White, A, Alonso, A R, Kay
openaire   +2 more sources