Results 191 to 200 of about 1,364 (219)
Retatrutide Shows Multiple Metabolic Benefits in Diet‐Induced Obese MASH Mouse and Hamster Models
Obesity, Volume 34, Issue S1, Page 43-53, June 2026.ABSTRACT Objective/Methods Our aim was to evaluate the efficacy of the triple glucagon, GIP, and GLP‐1 receptor agonist retatrutide in diet‐induced obese MASH mouse and hamster models, two preclinical models that we routinely use for assessing new therapies targeting obesity.
François Briand +6 more
wiley +1 more source
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Knee Surgery, Sports Traumatology, Arthroscopy, 2022
AbstractPurposeIn kinematically aligned total knee arthroplasty (TKA), it is necessary to infer the pre‐arthritic constitutional medial proximal tibial angle (MPTA) in advanced osteoarthritis (OA) of the knee with bone loss. The aim of this study was to investigate whether MPTA at the posterior tibial plateau represents the pre‐arthritic constitutional
Hiroyasu Ogawa +2 more
exaly +3 more sources
AbstractPurposeIn kinematically aligned total knee arthroplasty (TKA), it is necessary to infer the pre‐arthritic constitutional medial proximal tibial angle (MPTA) in advanced osteoarthritis (OA) of the knee with bone loss. The aim of this study was to investigate whether MPTA at the posterior tibial plateau represents the pre‐arthritic constitutional
Hiroyasu Ogawa +2 more
exaly +3 more sources
Knee Surgery, Sports Traumatology, Arthroscopy, 2018
The purpose of this study was to detect the pre- and intra-operative influential factors for lower limb alignment correction error in open-wedge high tibial osteotomy (OWHTO).This study involved 69 patients (71 knees) undergoing OWHTO for primary medial osteoarthritis.
Mitsuaki Kubota +2 more
exaly +3 more sources
The purpose of this study was to detect the pre- and intra-operative influential factors for lower limb alignment correction error in open-wedge high tibial osteotomy (OWHTO).This study involved 69 patients (71 knees) undergoing OWHTO for primary medial osteoarthritis.
Mitsuaki Kubota +2 more
exaly +3 more sources
Knee Surgery, Sports Traumatology, Arthroscopy, 2019
AbstractPurposeThis study examined the influence of the mechanical medial proximal tibial angle (MPTA) on anterior cruciate ligament (ACL) degeneration following open wedge high tibial osteotomy (OWHTO). It was hypothesised that an excessive increase in MPTA would be associated with ACL degeneration following OWHTO.MethodsSeventy‐four knees treated ...
Hiroyasu Ogawa +2 more
exaly +3 more sources
AbstractPurposeThis study examined the influence of the mechanical medial proximal tibial angle (MPTA) on anterior cruciate ligament (ACL) degeneration following open wedge high tibial osteotomy (OWHTO). It was hypothesised that an excessive increase in MPTA would be associated with ACL degeneration following OWHTO.MethodsSeventy‐four knees treated ...
Hiroyasu Ogawa +2 more
exaly +3 more sources
Clinical Biomechanics, 2020
Recurrent varus deformity and poor outcome sometimes occur following open-wedge high tibial osteotomy, but the mechanism remains unclear. The hypothesis of this study was that an excessively large medial proximal tibial angle with lateral joint surface inclination can worsen postoperative knee biomechanics.A computer-simulated knee model was validated ...
Shinichi Kuriyama +2 more
exaly +3 more sources
Recurrent varus deformity and poor outcome sometimes occur following open-wedge high tibial osteotomy, but the mechanism remains unclear. The hypothesis of this study was that an excessively large medial proximal tibial angle with lateral joint surface inclination can worsen postoperative knee biomechanics.A computer-simulated knee model was validated ...
Shinichi Kuriyama +2 more
exaly +3 more sources
International Orthopaedics, 2020
The purpose of this study was to evaluate changes of patellar height and posterior tibial slope angle following uniplanar medial opening wedge high tibial osteotomy using a novel wedge-shaped spacer implanation concurrent with proximal partial fibulectomy.All patients who underwent uniplanar medial opening wedge high tibial osteotomy using a novel ...
Xiangtian Deng +2 more
exaly +3 more sources
The purpose of this study was to evaluate changes of patellar height and posterior tibial slope angle following uniplanar medial opening wedge high tibial osteotomy using a novel wedge-shaped spacer implanation concurrent with proximal partial fibulectomy.All patients who underwent uniplanar medial opening wedge high tibial osteotomy using a novel ...
Xiangtian Deng +2 more
exaly +3 more sources
Arthroscopy - Journal of Arthroscopic and Related Surgery, 2019
Purpose To evaluate whether the overcorrected medial proximal tibial angle (MPTA) affects the clinical outcomes after open‐wedge high tibial osteotomy (OWHTO) and to assess the correlation between knee joint line obliquity (KJLO) changes and the compensatory changes in the hip and ankle joints.
Kenichi Goshima +2 more
exaly +3 more sources
Purpose To evaluate whether the overcorrected medial proximal tibial angle (MPTA) affects the clinical outcomes after open‐wedge high tibial osteotomy (OWHTO) and to assess the correlation between knee joint line obliquity (KJLO) changes and the compensatory changes in the hip and ankle joints.
Kenichi Goshima +2 more
exaly +3 more sources
Knee Surgery, Sports Traumatology, Arthroscopy
Abstract Purpose Unicompartmental knee arthroplasty (UKA) is increasingly used for isolated knee osteoarthritis. The medial proximal tibial angle (MPTA) is important for describing tibial alignment. However, MPTA measurement after UKA is challenging because one tibial compartment is prosthetic.
Mohammad Poursalehian +2 more
exaly +3 more sources
Abstract Purpose Unicompartmental knee arthroplasty (UKA) is increasingly used for isolated knee osteoarthritis. The medial proximal tibial angle (MPTA) is important for describing tibial alignment. However, MPTA measurement after UKA is challenging because one tibial compartment is prosthetic.
Mohammad Poursalehian +2 more
exaly +3 more sources