Results 231 to 240 of about 5,644,878 (284)

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Pre-CRRT furosemide and mortality in sepsis-associated AKI: A retrospective cohort study. [PDF]

PLoS One
Shen SY, Fu L, Liang DY, Wang SK, Chen H, Cao LJ, Yu WL, Sun Y, Lu ZH.   +8 more
europepmc   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Pivotal studies of pharmacotherapies approved by the US FDA for cancer treatment: a meta-analysis. [PDF]

Oncologist
Chow R, Im JHB, Zimmermann C, Richards GC, Heneghan C.   +4 more
europepmc   +1 more source

Neighborhood Indices, Income, and Cardiovascular-Kidney-Metabolic Syndrome at the Census Tract Level.

JAMA Netw Open
Krishnan V, Huang X, McGowan C, Shah NS, Qureshi F, Minkovitz CS, Kershaw KN, Freedman AA, Miller GE, Lloyd-Jones DM, Khan SS.   +10 more
europepmc   +1 more source

From Intensive Care to Recovery: Feasibility of a Randomised Controlled Study Design Evaluating a Cognitive Rehabilitation Intervention for Critically Ill Patients. [PDF]

Nurs Crit Care
Astrup K, Nedergaard HK, Dreyer P, Holm A, Møller M, Haberlandt TN, Sig R, Rolving N.   +7 more
europepmc   +1 more source

Planned time burden for patients participating in phase 2 cancer trials. [PDF]

Oncologist
Ouimet C, Iskander R, Nipp R, Kimmelman J.   +3 more
europepmc   +1 more source

CSF Aquaporin-4 levels in controls and in idiopathic normal pressure hydrocephalus before and after shunt surgery. [PDF]

Fluids Barriers CNS
De Ryst JE, Bergström S, Mravinacova S, Bäckström D, Qvarlander S, Månberg A, Eklund A, Malm J.   +7 more
europepmc   +1 more source

Healthcare resource utilization and cost burden of COVID-19 according to vaccination status in adults in Ontario, Canada, 2021-2023. [PDF]

PLoS One
McDonald C, Grajales AG, Yahia NA, Fisman D, Wang IY, Nightingale N, Neish CS, Nair S, Mustapha M, Yang J.   +9 more
europepmc   +1 more source