Results 61 to 70 of about 569,016 (270)

Winsorizing [PDF]

open access: yes, 2018
In lieu of an abstract, here is the entry\u27s first paragraph: Winsorizing is a procedure that moderates the influence of outliers on the mean and variance and thereby creates more robust estimators of location and variability.
Blaine, Bruce E
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Integrating PCA and Fractal Modeling for Identifying Geochemical Anomalies in the Tropics: The Malang–Lumajang Volcanic Arc, Indonesia

open access: yesGeosciences
Intense chemical weathering in tropical environments poses challenges for conventional geochemical exploration, as primary lithological signatures become heavily altered.
Wahyu Widodo   +14 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Orthoptic status before and immediately after heroin detoxification [PDF]

open access: yes, 2004
Aim: To determine whether changes in orthoptic status take place during withdrawal from heroin and/or methadone. Method: A prospective study of patients, using a repeated measures design, attending a 5 day naltrexone compressed opiate detoxification ...
Beaini, A.Y.   +3 more
core   +2 more sources

Control Charts for Monitoring Process Capability Index Using Median Absolute Deviation for Some Popular Distributions [PDF]

open access: yesProcesses, 2019
A control chart monitoring the process capability index (PCI) using median absolute deviation (MAD) is proposed to analyze the industrial process performance. Extensive simulation studies were carried out to evaluate the performance of MAD-based PCI control charts under the low, moderate, and high asymmetric conditions when the process characteristic ...
Muhammad Aslam   +4 more
openaire   +2 more sources

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Medicare part D prescribing for direct oral anticoagulants in the United States: Cost, use and the "rubber effect". [PDF]

open access: yesPLoS ONE, 2018
IntroductionDirect oral anticoagulants (DOAC) have gained an increased share over warfarin for prevention and treatment of thromboembolic disease. We studied DOAC adoption across providers and medical specialties.MethodsRetrospective, cross-sectional ...
Panayiotis D Ziakas   +4 more
doaj   +1 more source

Local Stellar Kinematics from RAVE data - VII. Metallicity Gradients from Red Clump Stars [PDF]

open access: yes, 2016
We investigate the Milky Way Galaxy's radial and vertical metallicity gradients using a sample of 47,406 red clump stars from the RAVE DR4. This sample is more than twice the size of the largest sample in the literature investigating radial and vertical ...
Ak, S.   +6 more
core   +2 more sources

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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