Results 81 to 90 of about 207,324 (261)

Benchmark study of three statistical methods for six intact rock failure criteria constrained by different rock strength data

open access: yesUnderground Space
To reduce the impact of potential strength outliers on parameter estimation, statistical methods based on the least median square and least absolute deviation have been proposed as alternatives to the traditional least square method.
Peng-fei He   +4 more
doaj   +1 more source

Quantitative assessment of polymetallic pollution of the dnieper river by a method of heavy metals background concentration calculation in mussel Anodonta anatina

open access: yesVìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Ekologìâ, 2009
Statistically significant exceeding of a background level of the heavy metal content in Anodonta anatina (Linnaeus, 1758) soft tissues was applied for pollution measure.
D. V. Lukashov
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

The Effect of Gingival Color on the Accuracy of Different Intraoral Scanners in Partially Edentulous Patients: An In Vitro Study

open access: yesApplied Sciences
Objective: This in vitro study evaluated the accuracy and precision of five intraoral scanners (IOSs) by examining the interaction between gingival model color and linear measurement distances.
Burak AK   +3 more
doaj   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

DA-IRRK: Data-Adaptive Iteratively Reweighted Robust Kernel-Based Approach for Back-End Optimization in Visual SLAM

open access: yesSensors
Back-end optimization is a key process to eliminate the cumulative error in Visual Simultaneous Localization and Mapping (VSLAM). Existing VSLAM frameworks often use kernel function-based back-end optimization methods.
Zhimin Hu   +5 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

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