Results 41 to 50 of about 10,919 (188)

When to consider an inborn error of immunity: clues for physicians

Internal Medicine Journal, EarlyView.
Abstract The term inborn errors of immunity (IEIs) refers to the rapidly expanding group of genetic disorders causing dysregulation of the immune system. With improved genetic testing in recent years, the number of defined IEIs and their range of phenotypic presentations has grown vastly, with more than 550 IEIs now described.
Meera Thangarajah, Lucinda J. Berglund
wiley   +1 more source

Recurrent Hemoptysis and a Mass in the Thorax in an Infant: The Split Notochord Syndrome

European Journal of Pediatric Surgery Reports, 2014
Split notochord syndrome is a rare group of developmental abnormalities caused by abnormal splitting or deviation of the notochord clinically resulting in the duplicated bowel associated with vertebral anomalies.
Mutlu Uysal Yazici, Saniye Ekinci, Ozlem Keskin Turkmen, Ebru Gunes Yalcin, Arbay O. Ciftci, Safak Gucer, Diclehan Orhan, Ilhan Tezcan   +7 more
doaj   +1 more source

Ectopic PTH-producing parathyroid cyst inside the thymus: a case report

BMC Endocrine Disorders, 2022
Background The hallmark of hyperparathyroidism is hypersecretion of parathyroid hormone (PTH) which results in hypercalcemia and hypophosphatemia.
Haruka Takenouchi, Takatoshi Anno, Ayaka Harada, Hayato Isobe, Yukiko Kimura, Fumiko Kawasaki, Kohei Kaku, Koichi Tomoda, Hideyo Fujiwara, Hideaki Kaneto   +9 more
doaj   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Clinical Remission of an Unresectable Presumptive Haemangiosarcoma in a Dog Treated With Toceranib, Piroxicam, and Propranolol: A Case Report

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Radiographic remission of a presumptive unresectable haemangiosarcoma treated with toceranib, piroxicam, and propranolol. In a dog with ACVIM Stage B2 myxomatous mitral valve disease where doxorubicin‐based chemotherapy was contraindicated, this multimodal regimen achieved marked tumour reduction and radiographic disappearance.
Woo Dae Park
wiley   +1 more source

Age‐ and gender‐specific disease distribution and the diagnostic accuracy of CT for resected anterior mediastinal lesions

Thoracic Cancer, 2019
Background Anterior mediastinal lesions account for approximately half of all mediastinal masses and computed tomography (CT) is known to exhibit limited differentiating performance.
Ju Gang Nam, Jin Mo Goo, Chang Min Park, Hyun‐Ju Lee, Chang Hyun Lee, Soon Ho Yoon   +5 more
doaj   +1 more source

Respiratory Organ‐on‐a‐Chip for Disease Modeling: From Architecture to Functional Integration

Advanced Healthcare Materials, Volume 15, Issue 23, 19 June 2026.
Respiratory organ‐on‐a‐chip (ROC) models capture key mechanical and cellular cues of the human respiratory system, enabling quantitative dissection of disease mechanisms. This review links ROC architectures to disease modeling, functional integration, and commercialization, and proposes a decision framework that aligns model complexity with mechanistic
Jinzhuo Hu, Yongjie Tang, Sidi Liu, Tao Xu, Qian Liu   +4 more
wiley   +1 more source

Case report: Mullerian cyst of mediastinum: report of two cases

Frontiers in Oncology
Posterior mediastinal Mullerian cyst is rare. Due to its special location, it is easy to be misdiagnosed clinically, imaging and pathologically. Imaging is often misdiagnosed as a bronchial cyst or neurogenic tumor. The postoperative misdiagnosis rate is
Aliye Abulizi, Aliye Abulizi, Yuan Yang, Peng An, Ping Gao   +4 more
doaj   +1 more source

Right Upper Lobe Pulmonary Spindle Cell Neoplasm With Rhabdoid Differentiation and Spinal Canal Invasion in a 19‐Year‐Old Female: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT We present an unusual case involving a 19‐year‐old female with progressive respiratory distress. Testing revealed pulmonary spindle cell neoplasms with rhabdoid features and spinal cord involvement and infectious complications, emphasizing the importance of multimodal imaging early for rare presentations, histopathological confirmation of ...
Quang Dai La, Aiman Baloch, Sobia Ahmed, Muhammad Ayub, Shanmukh Bachhu, Eric Teng, Hafsa Qayyum, Nam T. Nguyen   +7 more
wiley   +1 more source

Application of endoscopic ultrasound‐guided‐fine needle aspiration combined with cyst fluid analysis for the diagnosis of mediastinal cystic lesions

Thoracic Cancer, 2019
Background Mediastinal cystic lesions account for approximately 15–20% of all mediastinal masses and are difficult to differentiate because of similar imaging manifestation.
Yuchong Zhao, Ronghua Wang, Yun Wang, Qian Chen, Liangkai Chen, Wei Hou, Limin Liu, Wei Gao, Bin Cheng   +8 more
doaj   +1 more source