Results 181 to 190 of about 9,066,717 (393)
DomainScope: A disease network based on protein domain connections [PDF]
arXiv, 2019 Protein domains are highly conserved functional units of proteins. Because they carry functionally significant information, the majority of the coding disease variants are located on domains. Additionally, domains are specific units of the proteins that can be targeted for drug delivery purposes.
arxiv
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Diffuse large B‐cell lymphoma (DLBCL) exhibits substantial biological and clinical heterogeneity. This study investigated the expression and prognostic implications of C‐X‐C chemokine receptor type 5 (CXCR5) and lymphocyte activation gene‐3 (LAG‐3) on peripheral blood CD8+ T cells in patients with DLBCL.
Xi‐Zhe Guo, Ya‐Fei Guo, Shi‐Xin Wu
wiley +1 more source
Integrating cross-modality hallucinated MRI with CT to aid mediastinal lung tumor segmentation [PDF]
arXiv, 2019 Lung tumors, especially those located close to or surrounded by soft tissues like the mediastinum, are difficult to segment due to the low soft tissue contrast on computed tomography images. Magnetic resonance images contain superior soft-tissue contrast information that can be leveraged if both modalities were available for training.
arxiv
IgG4-related autoimmune disease : imaging findings [PDF]
, 2013 IgG4 autoimmune disease (or hyper IgG4 disease) is a relatively recently described systemic disease that is characterised by abundant infiltration of IgG4-positive plasma cells and lymphocytes with associated fibrosis leading to organ dysfunction ...
Vassallo, Pierre
core
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT It is challenging for radiologists to diagnose pulmonary metastases when they encounter only a few (n ≤ 5) small pulmonary nodules (< 10 mm) on staging CT in breast cancer patients. We conducted this study to assess clinical and imaging features related to metastasis for better risk stratification.
Huei‐Yi Tsai +7 more
wiley +1 more source
Brugada-type ECG associated with pectus excavatum [PDF]
, 2015 Brugada phenocopies (BrP) are new clinical entities characterized by an ECG pattern that is identical to type 1 or type 2 Brugada pattern, despite the absence of the true congenital Brugada syndrome (BrS).
Ghazali, Aiham +3 more
core +1 more source
ERJ Open ResearchBackground Sarcoidosis and tuberculosis (TB) are the two most common causes of granulomatous mediastinal lymphadenopathy. These often exhibit overlapping clinical and radiological characteristics, rendering accurate diagnosis difficult.
Bijay Pattnaik +12 more
doaj +1 more source
Association of SIRT6 Expression With Risk of Pneumonitis Induced by Radiotherapy in Cancer Patients
Molecular Carcinogenesis, EarlyView.ABSTRACT Thoracic tumours represent a significant proportion of malignant cancers. While radiotherapy (RT) improves prognosis, it can also lead to side effects such as radiation‐induced pneumonitis (RP). Since SIRT6 is involved in DNA repair, energy metabolism and inflammation, this study aims to investigate the expression of SIRT6 in lymphocytes as a ...
Fengyuan Yu +14 more
wiley +1 more source
SDF-Net: A Hybrid Detection Network for Mediastinal Lymph Node Detection on Contrast CT Images [PDF]
arXivAccurate lymph node detection and quantification are crucial for cancer diagnosis and staging on contrast-enhanced CT images, as they impact treatment planning and prognosis. However, detecting lymph nodes in the mediastinal area poses challenges due to their low contrast, irregular shapes and dispersed distribution.
arxiv
Surgery for non-small cell lung cancer with unsuspected metastasis to ipsilateral mediastinal or subcarinal nodes (N2 disease) [PDF]
, 1996 P DELEYN +6 more
openalex +1 more source