Results 101 to 110 of about 75,380 (266)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Anaesthetic considerations in a patient with an anterior mediastinal mass

open access: yes, 2013
We report a 35-year-old gentleman who presented to us with respiratory distress. He was diagnosed to have a large anterior mediastinal mass and was and posted for debulking of mediastinal mass.
M. H. Rao   +7 more
core  

Accessory thymus in posterior mediastinum

open access: yesJournal of Indian Association of Pediatric Surgeons, 2008
Presence of thymus in the normal position as well as in the posterior mediastinum is an unusual phenomenon. We report here a case of posterior mediastinal mass in a 20-month old male child who presented with dysphagia and dry cough.
Bhatnagar Sushmita   +3 more
doaj  

Anterior Mediastinal Mass [PDF]

open access: yesAnesthesiology, 2010
Ulrike Berth   +2 more
openaire   +2 more sources

Giant cell tumour of dorsal spine presenting with mediastinal mass: a rare case report

open access: yes, 2016
Incidence of giant cell tumour (GCT) of spine above sacrum is rare. Moreover, involvement of posterior elements of spine is a rare entity. Furthermore, primary GCT arising at thoracic spine presenting as a huge mediastinal mass is extremely rare.
Kalita, Chayanika   +3 more
core   +1 more source

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Unexpected Cervical Lymph Node Metastasis Revealing TFE3‐Rearranged Renal Cell Carcinoma: Intraoperative Cytologic Clues to an Occult Renal Primary

open access: yesDiagnostic Cytopathology, Volume 54, Issue 7, Page 538-541, July 2026.
ABSTRACT TFE3‐rearranged renal cell carcinoma (TFE3‐rRCC) is a rare subtype of renal carcinoma that may present diagnostic challenges in cytologic specimens, particularly when metastatic disease represents the initial clinical manifestation. We report the case of a 72‐year‐old man presenting with bulky cervical lymphadenopathy clinically suspicious for
Marc P. Pusztaszeri
wiley   +1 more source

Primary Solitary Mediastinal Mass Lesions: A Review of 37 Cases

open access: yes, 2006
Background: Primary solitary mass lesions of the mediastinum, although relatively uncommon, encompass an interesting spectrum of pathologies. Methods: A comprehensive retrospective review was undertaken of all cases of mediastinal lesions that presented ...
Bidstrup, Benjamin   +3 more
core   +1 more source

Metastatic Cutaneous Adnexal Carcinoma of the Head and Neck With Durable Response to an Aromatase Inhibitor Combined With a Cyclin‐Dependent Kinase 4/6 Inhibitor

open access: yesHead &Neck, Volume 48, Issue 7, Page E70-E75, July 2026.
ABSTRACT Background Cutaneous adnexal carcinomas are a very rare group of cancers arising from appendageal structures of the skin. More than half occur in the head and neck region. No standard treatments exist for metastatic disease. Methods A 48‐year‐old postmenopausal female presented with an enlarging scalp lesion.
Nilesh Kapoor   +3 more
wiley   +1 more source

Belzutifan for Metastatic TFE3‐Rearranged Renal Cell Carcinoma With Pulmonary Metastases: A Case Report

open access: yesIJU Case Reports, Volume 9, Issue 4, July 2026.
ABSTRACT Introduction Belzutifan is effective in patients with previously treated advanced clear cell renal cell carcinoma. However, evidence for its use in non‐clear cell renal cell carcinoma remains limited. Case Presentation A 33‐year‐old Japanese woman underwent total nephrectomy for a 10‐cm renal tumor with lung metastases.
Kazutaka Nakamura   +9 more
wiley   +1 more source

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