Results 201 to 210 of about 3,233,579 (289)

Clinical Characteristics and Novel Manometric Features of Pseudoachalasia: Identification of Loss of Respiratory Variation in Lower Esophageal Sphincter Pressure

open access: yesJGH Open, Volume 10, Issue 9, September 2026.
ABSTRACT Background Pseudoachalasia closely mimics idiopathic achalasia in both symptoms and high‐resolution manometry (HRM) findings, making accurate diagnosis difficult. This study aimed to clarify the clinical characteristics of pseudoachalasia encountered at our institution and identify novel manometric findings specific to this condition.
Eri Nishikawa   +11 more
wiley   +1 more source

Foreign body ingestions in children and adolescents: A position paper of the European Society for Pediatric Gastroenterology, Hepatology, and Nutrition (ESPGHAN) endoscopy special interest group

open access: yesJournal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 539-554, September 2026.
Abstract Foreign body (FB) ingestion is a relatively frequent occurrence in the pediatric population with multiple potential sequelae. Appropriate intervention may range from urgent endoscopic retrieval to watchful waiting, with multiple variables influencing the decision.
Oren Ledder   +18 more
wiley   +1 more source

Chronic hypoxia and mediastinal mass: think about a pulmonary artery to left atrial fistula! [PDF]

open access: yesJ Cardiol Cases
AbdelMassih AF   +5 more
europepmc   +1 more source

TLR7 Agonist Nanomedicine Suppresses Lung Metastasis of Osteosarcoma by Remodeling the Immune Microenvironment

open access: yesMedComm – Oncology, Volume 5, Issue 3, September 2026.
In tail‐vein and orthotopic osteosarcoma mouse models, 1V209‑Cho‑Lip, a TLR7 agonist liposome, effectively suppresses pulmonary metastasis and prolongs survival. Flow cytometry and single‑cell transcriptomics reveal that 1V209‑Cho‑Lip remodels both the pre‑metastatic and post‑metastatic immune microenvironments, alleviates myeloid‑mediated ...
Xinyue Zhang   +5 more
wiley   +1 more source

Oral GLP‐1RA TERN‐601 for Adults With Obesity/Overweight: Placebo‐Controlled, Multiple‐Ascending‐Dose, Phase 1 and 2 Studies

open access: yesObesity, Volume 34, Issue 9, Page 1742-1758, September 2026.
ABSTRACT Objective The safety, tolerability, pharmacokinetics, and efficacy of TERN‐601, a once‐daily, oral small‐molecule glucagon‐like peptide‐1 (GLP‐1) receptor agonist, were studied in Phase 1 and 2 clinical studies. Methods The Phase 1 (28‐day) and Phase 2 (12‐week), randomized, double‐blind, placebo‐controlled, multiple‐ascending‐dose studies ...
W. Timothy Garvey   +11 more
wiley   +1 more source

[Pulmonary stenosis due to a mediastinal mass: an uncommon cause]. [PDF]

open access: yesArch Cardiol Mex
López-Gutiérrez LV   +3 more
europepmc   +1 more source

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