Results 41 to 50 of about 3,233,579 (289)

Langerhans Cell Histiocytosis in an Infant Mimicking a Lymphoma at Presentation

open access: yesCase Reports in Hematology, 2015
Langerhans cell histiocytosis (LCH) is a rare disorder characterized by proliferation and accumulation of clonal dendritic cells with varied clinical presentation and an unpredictable course.
Anjan Madasu   +5 more
doaj   +1 more source

Multi‐Omics Integration Identifies a CDH3‐Associated Malignant Epithelial State and Immunosuppressive Niche to Predict Prognosis in Thymic Epithelial Tumors

open access: yesAdvanced Science, EarlyView.
Single‐cell, spatial, molecular, and pathology analyses identify a CDH3‐associated malignant epithelial state in thymic epithelial tumors. This state links stem‐like and EMT programs to M2 macrophage–rich immunosuppressive niches, genomic instability, poor survival, and drug vulnerability.
Yuntao Feng   +13 more
wiley   +1 more source

Mediastinal mass

open access: yesSouthwest Respiratory and Critical Care Chronicles, 2017
Rhabdomyosarcoma rarely presents as a mediastinal mass in adults.
Sakolwan Suchartlikitwong
doaj  

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

open access: yesAdvanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang   +10 more
wiley   +1 more source

An Unusual Cause of Mediastinal Mass — A Case Report and Literature Review of Intrathoracic Kidney

open access: yesProceedings of Singapore Healthcare, 2012
Posterior mediastinal mass is not an uncommon condition seen in clinical practice. It often generates anxiety among healthcare providers, as the most common cause of a posterior mediastinal mass is a neurogenic tumour which potentially can be malignant ...
Siew Le Chong MRCPCH (UK)   +1 more
doaj   +1 more source

Posthumously Diagnosed Myhre Syndrome Presenting With Pleural Remodeling and Endometrial Cancer

open access: yesAmerican Journal of Medical Genetics Part C: Seminars in Medical Genetics, EarlyView.
ABSTRACT Myhre syndrome (OMIM 139210) is a genetic condition defined by neurodevelopmental disability, characteristic facial features, and multisystem proliferative fibrosis. While various types of lung disease have been reported, pleural remodeling leading to restrictive lung disease has not yet been described.
Jeanette Saffir   +6 more
wiley   +1 more source

Giant residual non-seminonatous mediastinal mass [PDF]

open access: yes, 2004
PURPOSE: To point out the difficult therapeutic management of mediastinal germ-cell tumors and the residual masses. MATERIAL AND METHODS: We present a patient with a mediastinal non-seminomatous germ-cell tumor and the therapeutic management of the ...
Ocaña,A.   +4 more
core  

Robotic Resection of Large Anterior Mediastinal Mass

open access: yes, 2022
A giant mediastinal mass has traditionally been operated on using an open approach. However, a minimally invasive approach can be done with good results. Robotic surgery has been proven safe for mediastinal mass removal.
Jean Marc Baste (7037174)   +2 more
core   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé   +12 more
wiley   +1 more source

Primary mediastinal seminoma with florid follicular lymphoid hyperplasia: a case report and review of the literature

open access: yesDiagnostic Pathology, 2021
Background First described in 1955 Primary mediastinal seminomas are rare. Only 1–4% of mediastinal tumours are germ cell tumors; majority of which are teratomas. They typically present in men aged between 20 and 40 years.
Charlotte Holmes   +2 more
doaj   +1 more source

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