Results 161 to 170 of about 50,573 (248)

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, Volume 7, Issue 4, August 2026.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

The differences in CT findings between schwannoma in mediastinum and retroperitoneum. [PDF]

Medicine (Baltimore)
Yan Z, Lin Z, Feng S, Pan Y, Wang J, Kang J, Feng Z.   +6 more
europepmc   +1 more source

Effects of Bifidobacterium animalis Subsp. Lactis CP‐9 on Gut Microbiota and Immune Functions in Healthy Infants

Microbial Biotechnology, Volume 19, Issue 8, August 2026.
This study evaluated the 3‐month safety and tolerability of the probiotic CP‐9 in healthy infants aged 6 to 36 months. The research confirmed that, under the conditions of this study, CP‐9 can safely enrich specific beneficial bacterium in the gut without any obvious short‐term safety signal. ABSTRACT Infancy represents a critical period for growth and
Liujing Zhang, Xueke Song, Keming Zhang, Xiaoshuang Xu, Xinmei Guo, Wei Li, Xiaoling Zeng, Yingguang Xie, Liwei Nie, Li Zhao, Xuelu Dai, Jing Sun, Jiai Yan, Yiran Liu, Feng Zhang, Zhiping Sun   +15 more
wiley   +1 more source

Long-Term Survival After Desperation Surgery for Primary Mediastinal Non-Seminomatous Germ Cell Tumor With Rising Alpha-Fetoprotein. [PDF]

IJU Case Rep
Aigase T, Kishida T, Kubo H, Matsumoto T, Suzuki A, Washimi K, Okubo Y, Hara S, Sugiura H, Nakaigawa N.   +9 more
europepmc   +1 more source

A Noncanonical MET Exon 14 Splice‐Site Variant in Pulmonary Sarcomatoid Carcinoma With Response to Capmatinib

Thoracic Cancer, Volume 17, Issue 15, August 2026.
We describe a patient with pulmonary sarcomatoid carcinoma harboring a noncanonical MET splice donor–proximal indel, initially reported as a VUS, who achieved a rapid response to capmatinib. RNA sequencing and ddPCR confirmed exon 14 skipping, supporting orthogonal transcript‐level validation for exon‐adjacent variants. ABSTRACT MET exon 14 skipping is
Hyung‐Joo Oh, Yoo‐Duk Choi, Yoon‐La Choi, Ha‐Young Park, Joon‐Young Yoon, Jang‐Hyeon Kim, Jung‐Hwan Lim, Cheol‐Kyu Park, In‐Jae Oh, Young‐Chul Kim   +9 more
wiley   +1 more source

Ivonescimab monotherapy in an elderly patient with EGFR-TKI-resistant advanced lung adenocarcinoma and pericardial effusion: a case report and literature review. [PDF]

Front Immunol
Zhu C, Yu H, Gu Y, Jiang T.
europepmc   +1 more source

Probable sepsis‐associated encephalopathy as a component of multiple organ dysfunction syndrome in a cat with pyothorax

Australian Veterinary Journal, Volume 104, Issue 8, Page 523-531, August 2026.
A 2‐year‐old male neutered domestic shorthair cat with bacterial pyothorax was referred to a tertiary hospital for treatment of sepsis. He met criteria for multiple organ dysfunction syndrome and developed new‐onset neurological dysfunction subsequent to the development of sepsis.
CC Chan, CR Sharp, CJ Boyd
wiley   +1 more source

Primary Mediastinal Seminoma: A Diagnostic and Therapeutic Challenge With an Optimistic Outcome. [PDF]

Case Rep Oncol Med
Dos Santos Bueno S, Borin Previtale R, Rocha Alves M, Soares Faico-Filho K.   +3 more
europepmc   +1 more source

Metabolic heterogeneity‐based radiomic model predicts treatment outcomes of primary mediastinal B‐cell lymphoma patients in the IELSG37 study

British Journal of Haematology, Volume 209, Issue 2, Page 514-523, August 2026.
Summary Early identification of patients at risk of failing first‐line therapy remains a key challenge in primary mediastinal B‐cell lymphoma (PMBCL). This study assessed whether positron emission tomography (PET) radiomics could predict treatment outcomes in PMBCL.
L. Ceriani, L. Milan, L. Cascione, A. Di Rocco, I. Kryachok, A. J. Davies, A. Stathis, D. Rossi, P. W. M. Johnson, M. Martelli, E. Zucca   +10 more
wiley   +1 more source

Sequential EBUS-Guided Fine Needle Aspiration and Transbronchial Cryobiopsy for the Diagnosis of a Giant Mediastinal Lipoma: A Novel Intraoperative Pivot Strategy. [PDF]

Respirol Case Rep
Kanchustambham V, Bowker WE.
europepmc   +1 more source