Results 161 to 170 of about 193,741 (293)

Case Report - Idiopathic mediastinal fibrosis presenting as mediastinal compression syndrome

, 2005
Mediastinal compression syndrome is a commonly seen entity. Mediastinal compression, mostly due to a space-occupying lesion, is distinct and different from mediastinitis/mediastinal fibrosis, which could also lead to superior vena cava syndrome ...
Harsha R. Salkar, Prashant L. Patil
core  

Case Report: Diagnostic dilemma: rebound thymic hyperplasia mimicking mediastinal relapse following chemoimmunotherapy in pediatric jejunal Burkitt lymphoma. [PDF]

Front Immunol
Lin M, Zhang Z, Zhang H, Zhang D.
europepmc   +1 more source

Benign Mediastinal Neoplasm [PDF]

, 2020
openaire   +1 more source

Old disease, new twist

Journal of Hospital Medicine, Volume 21, Issue 11, Page 1305-1309, November 2026.
Abstract An 81‐year‐old man with a history of high‐grade urothelial carcinoma of the bladder and ureter on treatment with atezolizumab and tiragolumab presented to the emergency department with 5 months of malaise, generalized weakness, and fatigue and 2 weeks of subjective fevers. One month prior to presentation, he received an empiric 9‐day course of
Hadi Roudsari, Gurpreet Dhaliwal, Anand D. Jagannath, Alan H. Baik, Sam Brondfield   +4 more
wiley   +1 more source

Protein Lactylation in Cancer: From Mechanisms to Therapy

MedComm, Volume 7, Issue 11, November 2026.
Increased glycolysis and lactate accumulation promote histone and nonhistone protein lactylation, linking tumor metabolic reprogramming to treatment adaptation. Lactylation enhances DNA repair, suppresses antitumor immunity, strengthens antioxidant defenses, and facilitates cell‐cycle checkpoint escape, collectively promoting resistance to chemotherapy,
Wentian Huang, Ping Hu, Shun Wang, Xide Zhang, Ziran Ye, Shengqiang Chen, Fu Gao, Yuanyuan Chen, Yanyong Yang   +8 more
wiley   +1 more source

Primary Mediastinal Germ Cell Tumor in a Woman Presenting With Superior Vena Cava Syndrome: A Case Report.

Mediastinal germ cell tumors (MGCTs) are rare neoplasms that typically occur in young men, with nonseminomatous subtypes predominating in this population.
Milian Cardoso, Oscar, Lorenz, Nicholas, Abouafech, Alex, Stauffer, John   +3 more
core   +1 more source

Multiple surgical excision for bilateral multiple mediastinal liposarcoma: a case report. [PDF]

J Surg Case Rep
Jiang S, Wang Z, Zhao J, Han Y, Shi H.
europepmc   +1 more source

Regulatory T Cells in Health and Disease

MedComm, Volume 7, Issue 11, November 2026.
Regulatory T cells (Tregs) arise through distinct developmental pathways and adapt to specialized tissue niches to maintain immune tolerance, barrier integrity, and metabolic homeostasis. In disease, Tregs undergo context‐dependent changes, ranging from functional insufficiency and lineage instability in autoimmune, inflammatory, cardiovascular, and ...
Mingyi Li, Si Zhang, Tangchun Wu, Tingting Tang, Xiang Cheng   +4 more
wiley   +1 more source

Anterior Mediastinal Germ Cell Tumor Presenting With Superior Vena Cava Obstruction and Malignant Pericardial Effusion. [PDF]

Cureus
Obied HY, Alsharif N, Ahmed EM, Noman A, Almahaid MA, Alkusataban FS, Raziq T.   +6 more
europepmc   +1 more source

Safety, Efficacy, and Pharmacokinetics of Unecritinib (TQ‐B3101) in Pediatric Patients With Relapsed/Refractory Anaplastic Lymphoma Kinase‐Positive Anaplastic Large‐Cell Lymphoma: A Phase I Study

MedComm, Volume 7, Issue 11, November 2026.
This Phase I study evaluated unecritinib (TQ‐B3101) in pediatric patients with relapsed/refractory ALK+ anaplastic large‐cell lymphoma. Unecritinib showed a manageable safety profile without dose‐limiting toxicities and achieved remarkable efficacy, with a 100% overall response rate.
Suying Lu, Junting Huang, Ruiqing Cai, Yan Gao, Jia Zhu, Juan Wang, Yi Que, Zijun Zhen, Feifei Sun, Huiqiang Huang, Yizhuo Zhang   +10 more
wiley   +1 more source