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Klinefelter's syndrome associated with mediastinal germ cell neoplasms.
Journal of Clinical Oncology, 1987Several case reports have suggested an association of primary mediastinal germ cell tumor (PMGCT) and Klinefelter's syndrome (KS). In an effort to confirm this association, 22 patients with mediastinal germ cell tumors had chromosome studies performed in a prospective fashion. Five patients (22%) had karyotypic or pathologic evidence of KS. All of the
Patrick J. Loehrer +5 more
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2019
neoplasms and lymphoma characteristically affect the anterior mediastinum while neurogenic neoplasms typically occur in the paravertebral regions. Patients with mediastinal neoplasms may be asymptomatic or may present because of symptoms of compression or local invasion.
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neoplasms and lymphoma characteristically affect the anterior mediastinum while neurogenic neoplasms typically occur in the paravertebral regions. Patients with mediastinal neoplasms may be asymptomatic or may present because of symptoms of compression or local invasion.
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Robotic and thoracoscopic surgeries for anterior mediastinal neoplasms
Pirogov Russian Journal of SurgeryObjective. To evaluate the efficacy and safety of robot-assisted (RATS) and video-assisted thoracoscopic (VTS) minimally invasive surgeries for anterior mediastinal neoplasms. Material and methods. The study involved 74 patients who underwent surgeries for anterior mediastinal neoplasms between 2020 and 2023.
Z.A. Bagatelia +7 more
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Primary mediastinal malignant germ cell neoplasms: imaging features
Chest Surgery Clinics of North America, 2002Mature teratomas are the most frequent primary mediastinal GCN. These are spherical multilocular cystic masses with thin, soft tissue septa and frequent internal fat attenuation. Primary mediastinal malignant GCNs are rare and should be included in the differential diagnosis of anterior mediastinal masses in young adult males.
Melissa L. Rosado-de-Christenson +1 more
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Klinefelter's syndrome associated with testicular microlithiasis and mediastinal germ‐cell neoplasm
Journal of Clinical Ultrasound, 1997Klinefelter's syndrome is a genetic disorder of male sexual differentiation characterized by an XXY karyotype. Although considered a benign condition, it is associated with several types of malignancies, including mediastinal germ-cell neoplasm. In addition, Klinefelter's syndrome has been rarely associated with testicular microlithiasis.
Robert I. Aizenstein +4 more
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A Remarkable Case of Mediastinal Neoplasm [PDF]
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Spatiotemporal distribution of mediastinal neoplasms: A comprehensive multi-center study
Lung CancerMediastinal neoplasms are typical but uncommon thoracic diseases with increasing incidence and unfavorable prognoses. A comprehensive understanding of their spatiotemporal distribution is essential for accurate diagnosis and timely treatment. However, previous studies are limited in scale and data coverage.
Yu Jiang +27 more
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