Results 271 to 280 of about 1,318,585 (312)
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Nebivolol: Endothelium-Mediated Vasodilating Effect
Journal of Cardiovascular Pharmacology, 2001Nebivolol, a racemic mixture of (S,R,R,R) and (R,S,S,S) enantiomers, is the most beta1-selective adrenoceptor antagonist currently available for clinical use. However, its haemodynamic effects differ from those of classical beta-adrenoceptor antagonists as a result of a vasodilating action.
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Nonplatelet-mediated effects of aspirin
Drugs of Today, 2002Aspirin has nonplatelet-mediated effects that contribute to its efficacy in the primary and secondary prevention of coronary events. These include antiarrhythmic effects, as shown in animal studies, and antiatherosclerotic effects related to increase in nitric oxide synthesis/activity and reduction in inflammatory mediators.
Y Wady, Aude, J L, Mehta
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Statistical assessment of mediational effects for logistic mediational models
Statistics in Medicine, 2004AbstractThe concept of mediation has broad applications in medical health studies. Although the statistical assessment of a mediational effect under the normal assumption has been well established in linear structural equation models (SEM), it has not been extended to the general case where normality is not a usual assumption. In this paper, we propose
Bin, Huang +3 more
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Estimation of the mediation effect with a binary mediator
Statistics in Medicine, 2006AbstractA mediator acts as a third variable in the causal pathway between a risk factor and an outcome. In this paper, we consider the estimation of the mediation effect when the mediator is a binary variable. We give a precise definition of the mediation effect and examine asymptotic properties of five different estimators of the mediation effect. Our
Yan, Li +2 more
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CGRP-mediated cardiovascular effect of nitroglycerin
Medical Hypotheses, 2003Organic nitrates, including nitroglycerin, produce vascular relaxation by releasing nitric oxide in vascular tissues near the plasma member of smooth muscle cells of veins and arteries. Calcitonin gene-related peptide (CGRP), a major transmitter in capsaicin-sensitive sensory nerves, is widely distributed in cardiovascular tissues and the release of ...
Yuan Jian, Li, Yan Hua, Du
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Antioxidant Effects on Cell-Mediated Immunity
Journal of Leukocyte Biology, 1985Abstract Experiments were performed to determine the effects of dietary selenium and/or vitamin E deficiency on cell-mediated cytotoxicity in the mouse. Natural killer cell-mediated cytotoxicity (NKCC) was depressed after 8 wk on diets deficient in selenium and/or vitamin E.
H C, Meeker +4 more
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Aspects of beneficial endotoxin-mediated effects
Klinische Wochenschrift, 1982The status of hyperreactivity and hyporeactivity following the administration of endotoxin in a susceptible host represents phenomena which are of interest in an attempt to understand the role of endotoxins in pathophysiological events in general. Two experimental approaches designed to examine these events are reported herein; i.v.
R, Urbaschek, B, Urbaschek
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Cytokine mediated effects in mucosal immunity
Immunology & Cell Biology, 1995SummaryThe predominance of IgA antibodies in mucosal sites reflects a combination of high rate IgA isotype switching among precursor cells in induction sites, their selective localization in mucosal effector tissues and vigorous proliferation of these cells after extravasation.
D R, Kramer +3 more
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Mediator style and mediation effectiveness
Negotiation Journal, 1986Jeanne M. Brett +2 more
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Physica A, 2016
Statistical mechanics has proven to be able to capture the fundamental rules underlying phenomena of social aggregation and opinion dynamics, well studied in disciplines like sociology and psychology. This approach is based on the underlying paradigm that the interesting dynamics of multi-agent systems emerge from the correct definition of few ...
Vilone, Daniele +3 more
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Statistical mechanics has proven to be able to capture the fundamental rules underlying phenomena of social aggregation and opinion dynamics, well studied in disciplines like sociology and psychology. This approach is based on the underlying paradigm that the interesting dynamics of multi-agent systems emerge from the correct definition of few ...
Vilone, Daniele +3 more
openaire +1 more source