Results 161 to 170 of about 1,930,794 (341)

The effects of teacher competence on student outcomes in elementary science education: The mediating role of teaching quality

open access: green, 2019
Benjamin Fauth   +6 more
openalex   +2 more sources

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Methodological guidelines for a rapid appraisal of agricultural innovation systems under agroecology (RAAIS-AE)

open access: yesFrontiers in Sustainable Food Systems
The agricultural innovation system (AIS) is an approach that considers agricultural innovation from a multidisciplinary perspective. The Rapid Appraisal of Agricultural Innovation Systems is one of the commonly used operational methods.
Hassen Ouerghemmi   +5 more
doaj   +1 more source

Mediation and Anti-Mediation

open access: yesJournal of Human-Technology Relations
The paper claims that traditional postphenomenology has not fully acknowledged the significance of breakdowns and anomalies in technology, as it is overly influenced by Heidegger's tool analysis and the dichotomy between ready-to-hand and present-at-hand.
openaire   +1 more source

Down-regulation of the expression of endothelial NO synthase is likely to contribute to glucocorticoid-mediated hypertension

open access: green, 1999
Thomas Wallerath   +9 more
openalex   +2 more sources

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Role of Bile Acids and GLP-1 in Mediating the Metabolic Improvements of Bariatric Surgery [PDF]

open access: bronze, 2018
Vance L. Albaugh   +9 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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